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直肠癌术后急性感染性暴发性紫癜合并细菌移位:1例报告

Acute Infectious Purpura Fulminans Complicated by Bacterial Translocation after Rectal Cancer Surgery: A Case Report.

作者信息

Nakanishi Ryo, Ozawa Heita, Toyota Naoyuki, Mise Minori, Akutsu Ritsuto, Fujita Shin

机构信息

Department of Colorectal Surgery, Tochigi Cancer Center, 4-9-13 Yohnan, Utsunomiya 320-0834, Japan.

出版信息

Medicina (Kaunas). 2024 Apr 17;60(4):644. doi: 10.3390/medicina60040644.

Abstract

The patient was a man in his 80s who had undergone laparoscopic anterior resection for rectal cancer. Bowel obstruction occurred on the third postoperative day but improved with a decompression tube by the fifth postoperative day. A high fever (in the 38 °C range) was also observed. Blood culture tests detected two sets of the gram-negative bacilli within 24 h of collection. On the seventh postoperative day, the patient subsequently went into septic shock with disseminated intravascular coagulation (DIC). On the eighth postoperative day, the fingertips and toes became black, and the palms and dorsal surfaces of both feet were dark purple due to peripheral circulatory failure. This suggested acute infectious purpura associated with sepsis (acute infectious purpura fulminans (AIPF)). Intensive care was provided; however, the necrosis of both middle fingers worsened, both middle fingers were gangrenous, and the patient died on the thirtieth postoperative day. AIPF is rarely reported, especially in early-onset cases after elective surgery. We encountered a rare complication of bacterial translocation from postoperative bowel obstruction, leading to AIPF.

摘要

该患者为一名80多岁的男性,曾接受直肠癌腹腔镜前切除术。术后第三天出现肠梗阻,但术后第五天通过减压管病情有所改善。还观察到高烧(38摄氏度左右)。血培养检测在采集后24小时内发现两组革兰氏阴性杆菌。术后第七天,患者随后出现感染性休克并伴有弥散性血管内凝血(DIC)。术后第八天,由于外周循环衰竭,指尖和脚趾变黑,双脚掌和足背呈深紫色。这提示与败血症相关的急性感染性紫癜(急性暴发性感染性紫癜(AIPF))。给予了重症监护;然而,双手中指坏死加重,双手中指坏疽,患者于术后第三十天死亡。AIPF很少被报道,尤其是在择期手术后的早期发病病例中。我们遇到了术后肠梗阻导致细菌移位进而引发AIPF的罕见并发症。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a593/11051725/4b749a644ff0/medicina-60-00644-g001.jpg

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