Christiansen Claus Behrend, Berg Ronan M G, Plovsing Ronni R, Møller Kirsten
Centre of Inflammation and Metabolism, Department of Infectious Diseases, Rigshospitalet, Copenhagen Ø, Denmark.
Scand J Infect Dis. 2012 Aug;44(8):635-9. doi: 10.3109/00365548.2012.672765. Epub 2012 Apr 12.
We report 2 cases of Capnocytophaga canimorsus-induced septicaemia complicated by purpura fulminans in previously healthy individuals, both of whom had been exposed to dog saliva prior to disease. They both presented with purpuric skin lesions, as well as the tetrad of abdominal symptoms, haemolytic anaemia, metabolic acidosis, and renal failure, which may be common in C. canimorsus-associated purpura fulminans. The patients survived after treatment with broad-spectrum antibiotics and supportive intensive care. C. canimorsus should be considered as a possible cause of infectious purpura fulminans in the unresolved critically ill patient with a history of dog exposure.
我们报告了2例犬咬二氧化碳嗜纤维菌引起的败血症病例,这2例既往健康的个体均在发病前接触过犬类唾液,且均并发暴发性紫癜。他们都出现了紫癜性皮肤病变,以及腹部症状、溶血性贫血、代谢性酸中毒和肾衰竭这一组四联征,这在犬咬二氧化碳嗜纤维菌相关的暴发性紫癜中可能较为常见。患者经广谱抗生素治疗及支持性重症监护后存活。对于有犬类接触史且病因不明的重症患者,应考虑犬咬二氧化碳嗜纤维菌是感染性暴发性紫癜的可能病因。