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通过细胞减灭术和腹腔内热灌注化疗(CRS-HIPEC)成功治疗腹膜假黏液瘤(PMP):一例病例报告及文献综述。

Successful treatment of pseudomyxoma peritonei (PMP) through cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (CRS-HIPEC): A case report and literature review.

作者信息

Awad Areej, Awad Mahmoud, Alami Muayyad, Sablan Aseel Abu, Shrateh Oadi N, Jubran Fahmi

机构信息

Faculty of Medicine, Al-Quds University, Jerusalem, Palestine.

Faculty of Medicine, Al-Quds University, Jerusalem, Palestine.

出版信息

Int J Surg Case Rep. 2024 Jun;119:109656. doi: 10.1016/j.ijscr.2024.109656. Epub 2024 Apr 20.

DOI:10.1016/j.ijscr.2024.109656
PMID:38677258
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11067356/
Abstract

INTRODUCTION AND IMPORTANCE

Pseudomyxoma peritonei (PMP) is characterized by the accumulation of mucinous fluid in the abdominal cavity, typically originating from mucin-producing tumors, most commonly arising in the appendix.

CASE PRESENTATION

A 63-year-old male patient presented to the hospital with complaints of abdominal pain, significant weight loss, a palpable mass in the right iliac fossa, and evidence of ascites. A diagnosis of PMP was proposed based on findings from a computed tomography (CT) scan, which was subsequently confirmed through histopathological examination of a biopsy. The patient underwent successful treatment with Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy (CRS-HIPEC).

CLINICAL DISCUSSION

Diagnosing PMP presents challenges due to its rarity and the potential for extensive spread throughout the peritoneal cavity, necessitating a multidisciplinary approach for successful treatment.

CONCLUSION

Pseudomyxoma peritonei is a rare yet medically significant condition. Documenting a case of this ailment in Palestine has the potential to advance medical understanding, raise awareness, and improve patient care standards within the local healthcare system. By documenting this uncommon condition, healthcare practitioners in Palestine can gain valuable insights into its manifestations, diagnostic processes, and treatment modalities. This contribution not only enriches the global medical literature but also promotes collaboration in addressing the challenges associated with rare diseases.

摘要

引言与重要性

腹膜假黏液瘤(PMP)的特征是腹腔内积聚黏液性液体,通常源于产生黏液的肿瘤,最常见于阑尾。

病例介绍

一名63岁男性患者因腹痛、体重显著减轻、右下腹可触及肿块及腹水迹象入院。根据计算机断层扫描(CT)结果提出PMP诊断,随后经活检组织病理学检查得以证实。该患者接受了减瘤手术及腹腔内热灌注化疗(CRS-HIPEC)并获得成功治疗。

临床讨论

由于PMP罕见且可能在整个腹腔广泛扩散,其诊断存在挑战,因此成功治疗需要多学科方法。

结论

腹膜假黏液瘤是一种罕见但具有医学重要性的疾病。在巴勒斯坦记录该疾病病例有可能增进医学认识、提高认识并改善当地医疗系统内的患者护理标准。通过记录这种罕见疾病,巴勒斯坦的医疗从业者可以深入了解其表现、诊断过程和治疗方式。这一贡献不仅丰富了全球医学文献,还促进了在应对罕见疾病相关挑战方面的合作。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/70f7/11067356/467a570be48f/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/70f7/11067356/17289e20c256/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/70f7/11067356/fb89cf12f2b6/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/70f7/11067356/467a570be48f/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/70f7/11067356/17289e20c256/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/70f7/11067356/fb89cf12f2b6/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/70f7/11067356/467a570be48f/gr3.jpg

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