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编辑评论:自体和异体骨软骨移植对高级别髋关节股骨软骨损伤显示出良好的效果,但对于撞击伤和骨坏死需要谨慎。

Editorial Commentary: Osteochodral Autograft and Allograft Show Favorable Outcomes for High-Grade Hip Femoral Cartilage Lesions, but Caution Is Required for Impaction Injuries and Osteonecrosis.

作者信息

Beck Edward C, Trasolini Nicholas A

出版信息

Arthroscopy. 2025 Feb;41(2):374-376. doi: 10.1016/j.arthro.2024.03.048. Epub 2024 Apr 25.

DOI:10.1016/j.arthro.2024.03.048
PMID:38677565
Abstract

Articular cartilage defects of the hip pose therapeutic challenges. Among patients undergoing hip arthroscopy for femoroacetabular impingement syndrome, more than 20% may have partial- or full-thickness chondral damage, and patients with high-grade (International Cartilage Repair Society grade 3 or 4) damage who undergo arthroscopic treatment of femoroacetabular impingement syndrome have higher rates of reoperation at 10-year follow-up. Arthroscopic and open techniques have been developed to translate cartilage restoration options initially developed in the knee for use in the hip. Arthroscopic options include chondroplasty, microfracture, biologic cartilage scaffolds, autologous chondrocyte implantation, and minced cartilage autograft (albeit more commonly in the acetabulum than the femoral head). Open techniques include autologous chondrocyte grafting, osteochondral autograft transfer (including mosaicplasty), osteochondral allograft transplantation, and arthroplasty. Open osteochondral allograft and autograft transplantation show improved patient-reported outcomes and forestall arthroplasty in young patients with high-grade cartilage defects of the femoral head. A recent review shows survivorship of 70% to 87.5% for allograft and 61.5% to 96% for autograft. At the same time, outcomes are not universally positive, particularly for patients with posttraumatic impaction injuries and high-grade osteonecrosis. Until further data better clarify the indications and contraindications, widespread adoption of open cartilage transplantation to the femoral head should be approached with caution, especially for older patients, in whom the gold standard of total hip arthroplasty has excellent survivorship at long-term follow-up.

摘要

髋关节的关节软骨缺损带来了治疗挑战。在因股骨髋臼撞击综合征接受髋关节镜检查的患者中,超过20%可能存在部分或全层软骨损伤,而接受股骨髋臼撞击综合征关节镜治疗的高级别(国际软骨修复协会3级或4级)损伤患者在10年随访时的再次手术率更高。已经开发出关节镜和开放技术,以将最初在膝关节中开发的软骨修复方法应用于髋关节。关节镜治疗方法包括软骨成形术、微骨折术、生物软骨支架、自体软骨细胞植入和碎软骨自体移植(尽管在髋臼比股骨头更常用)。开放技术包括自体软骨细胞移植、骨软骨自体移植转移(包括镶嵌成形术)、骨软骨异体移植和关节成形术。开放的骨软骨异体移植和自体移植在年轻的股骨头高级别软骨缺损患者中显示出改善的患者报告结局并延缓了关节成形术。最近的一项综述显示,异体移植的生存率为70%至87.5%,自体移植为61.5%至96%。与此同时,结果并非普遍良好,特别是对于创伤后撞击伤和高级别骨坏死患者。在进一步的数据更好地阐明适应症和禁忌症之前,对于股骨头开放软骨移植的广泛应用应谨慎对待,尤其是对于老年患者,在这些患者中,全髋关节置换术的金标准在长期随访中具有出色的生存率。

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