Texas Children's Hospital Houston, TX, United States; Baylor College of Medicine Houston, TX, United States.
Texas Children's Hospital Houston, TX, United States; Baylor College of Medicine Houston, TX, United States.
Semin Pediatr Neurol. 2024 Apr;49:101119. doi: 10.1016/j.spen.2024.101119. Epub 2024 Feb 15.
Clinical pharmacists are a part of the integrated health care team and provide valuable input on medication management for patients with acute and chronic disease states. Using epilepsy as a model, pharmacist involvement in patient care has been associated with significant reductions in monthly seizure frequency. Given differences in etiology, pediatric patients with epilepsy are likely to have higher number of treatments, with additional pharmacodynamic and pharmacokinetic differences, adding to the importance of utilizing a pediatric clinical pharmacist practitioner with neuropharmacology expertise. There is an increasing exposure to critically ill patients with epilepsy and other neurological disorders in the pediatric intensive care unit (PICU). These patients are more medically complex, increasing the risk for medication errors and increased health care costs. Emphasis on neurocritical care education is a vital component to improving patient outcomes. Inclusion of a clinical pharmacist practitioner in these settings yields a positive impact on major health outcomes. In 2018, the Neurocritical Care Society developed consensus recommendations on the standards for the development of adult neurocritical care units. A pharmacist-delivered pediatric critical care neuropharmacology rotation represents a novel approach to expanding physician education to improve patient outcomes. While there are sparse publications highlighting the importance of adult critical care and NCC pharmacists, no such literature exists describing the benefits of pediatric neurocritical care (PNCC) pharmacists. To the best of our knowledge, this is the first manuscript describing the role of clinical pharmacist practitioners in the development of PNCC program and the benefits they provide to patient care and education.
临床药师是综合医疗团队的一部分,为急性和慢性病患者的药物管理提供有价值的建议。以癫痫为例,药师参与患者护理与每月癫痫发作频率的显著降低有关。鉴于病因的差异,患有癫痫的儿科患者可能需要接受更多的治疗,同时还存在药代动力学和药效学的差异,因此利用具有神经药理学专业知识的儿科临床药师来进行治疗非常重要。儿科重症监护病房(PICU)中越来越多地接触到患有癫痫和其他神经障碍的重症患者。这些患者的病情更为复杂,增加了用药错误和医疗费用增加的风险。重视神经危重症教育是改善患者预后的重要组成部分。在这些环境中纳入临床药师实践人员对主要健康结果有积极影响。2018 年,神经危重症学会制定了关于成人神经危重症监护单位发展标准的共识建议。药剂师提供儿科危重病神经药理学轮转是一种扩展医师教育以改善患者预后的新方法。虽然有一些关于成人危重病和 NCC 药剂师重要性的出版物,但没有描述儿科神经危重病(PNCC)药剂师的好处的文献。据我们所知,这是第一篇描述临床药师在 PNCC 项目发展中的作用以及他们为患者护理和教育提供的好处的论文。