帕金森病可能的临床诊断方法的研究进展：事件相关电位。
Developments of possible clinical diagnostic methods for parkinson's disease: event-related potentials.
机构信息
Vocational School of Health Services/Istanbul, Altinbas University, Turkey.
Faculty of Medicine, Department of Neurology/Istanbul, Altinbas University, Turkey.
出版信息
Neurocase. 2023 Jun;29(3):67-74. doi: 10.1080/13554794.2024.2345404. Epub 2024 Apr 27.
In this study, Event-Related Potential (ERP) analyzes were performed to detect cognitive impairments in PD with Deep Brain Stimulation (DBS). A total of 85 volunteers underwent ERP analysis and neuropsychological testing (NPT) to determine cognitive level. In ERP analyses, prolonged latencies were observed in PD groups. However, patients implanted with DBS showed a decrease in latencies, a decrease in symptoms and statistical improvements in both cognitive and attention skills. Considering all these data, ERP results are promising as a noninvasive method that can be used in both disease status and diagnosis of PD.
在这项研究中，我们进行了事件相关电位（ERP）分析，以检测接受深部脑刺激（DBS）治疗的帕金森病（PD）患者的认知障碍。共有 85 名志愿者接受了 ERP 分析和神经心理学测试（NPT），以确定认知水平。在 ERP 分析中，PD 组观察到潜伏期延长。然而，接受 DBS 植入的患者潜伏期缩短，症状减轻，认知和注意力技能均有统计学改善。考虑到所有这些数据，ERP 结果很有希望成为一种非侵入性方法，可用于 PD 的疾病状态和诊断。
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