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新鲜骨软骨同种异体移植治疗大距骨骨软骨病变。

Fresh Osteochondral Allograft for Large Talar Osteochondral Lesions.

机构信息

Department of Orthopaedics, Medical University of South Carolina, Charleston, SC 29403, USA.

Department of Orthopaedics, Palomar Health Medical Group, 15611 Pomerado Road, Poway, CA 92064, USA.

出版信息

Foot Ankle Clin. 2024 Jun;29(2):343-356. doi: 10.1016/j.fcl.2023.07.009. Epub 2023 Sep 14.

Abstract

Osteochondral lesions of the talus are being recognized as an increasingly common injury. Large osteochondral lesions have significant biomechanical consequences and often require resurfacing with both boney and cartilaginous graft. The current treatment options include osteochondral autograft transfer, mosaicplasty, autologous chondrocyte implantation, or osteochondral allograft transplantation. Allograft procedures have the advantage of no donor site morbidity and ability to match the defect line to line. Careful transportation, storage, and handling of the allograft are critical to success. The failure of nonoperative management, failure of arthroscopic treatment, or large defects are an indication for resurfacing.

摘要

距骨骨软骨损伤正逐渐被认为是一种常见的损伤。大的骨软骨损伤有明显的生物力学后果,通常需要进行骨和软骨移植物的表面置换。目前的治疗选择包括骨软骨自体移植、马赛克plasty、自体软骨细胞移植或同种异体骨移植移植。同种异体移植物的手术具有无供体部位发病率和能够使缺陷线与线匹配的优点。同种异体移植物的小心运输、储存和处理对成功至关重要。非手术治疗失败、关节镜治疗失败或大的缺陷是表面置换的指征。

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