Postgraduate Program in Nursing, Federal University of Paraná, Curitiba, Paraná, Brazil.
Department of Nursing, Federal University of Paraná, Curitiba, Paraná, Brazil.
Asian Pac J Cancer Prev. 2024 Apr 1;25(4):1135-1141. doi: 10.31557/APJCP.2024.25.4.1135.
This study aimed to assess anxiety levels among women with metastatic breast cancer undergoing palliative chemotherapy.
A descriptive, prospective study was conducted at an oncology hospital in southern Brazil from September 2021 to October 2022. A total of 123 adult women receiving outpatient palliative chemotherapy were included in the study. Anxiety levels were evaluated using the State-Trait Anxiety Inventory at baseline, the fifth week, and the eleventh week of treatment. Data were analyzed using Kruskal-Wallis, Mann-Whitney, and Multiple General Regression Models.
Women with advanced breast cancer had an average trait-anxiety score of 48.24±5.92. A progressive improvement in anxiety scores was observed throughout the treatment evaluation stages (44.90±5.89; 43.37±5.34; 42.58±5.75), with a significant difference between the evaluations (p=0.008). Significant correlations were found between trait-anxiety and work situation (p=0.010) and ovarian metastasis (p=0.022). The adjusted general regression model also showed statistical significance for baseline evaluation with offspring (p=0.045) and education level (p=0.041).
Women with breast cancer undergoing palliative chemotherapy exhibited high trait-anxiety scores, which decreased significantly over the course of treatment.
本研究旨在评估接受姑息化疗的转移性乳腺癌女性的焦虑水平。
本研究为 2021 年 9 月至 2022 年 10 月在巴西南部一家肿瘤医院进行的描述性、前瞻性研究。共纳入 123 名接受门诊姑息化疗的成年女性。在基线、第 5 周和第 11 周治疗时使用状态-特质焦虑量表评估焦虑水平。使用 Kruskal-Wallis、Mann-Whitney 和多元广义回归模型进行数据分析。
晚期乳腺癌女性的特质焦虑平均得分为 48.24±5.92。在治疗评估阶段，焦虑评分逐渐改善（44.90±5.89；43.37±5.34；42.58±5.75），各评估之间差异有统计学意义（p=0.008）。特质焦虑与工作状况（p=0.010）和卵巢转移（p=0.022）呈显著相关。调整后的一般回归模型还显示，在基线评估时，与子女（p=0.045）和教育程度（p=0.041）呈统计学显著相关。
接受姑息化疗的乳腺癌女性表现出较高的特质焦虑评分，在治疗过程中显著降低。
