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美国粟粒性肺结核继发下消化道出血的罕见病例

Rare Case of Lower Gastrointestinal Bleeding Secondary to Miliary Tuberculosis in the United States.

作者信息

Sekh Marta B, Jack Alexa B, Rowe Danielle A, Henderson Nitori G, Zemaitis Michael R

机构信息

Medicine, College of Medicine, American University of Antigua, Osbourn, ATG.

Medicine, St. George's University School of Medicine, St. George's, GRD.

出版信息

Cureus. 2024 Mar 29;16(3):e57177. doi: 10.7759/cureus.57177. eCollection 2024 Mar.

Abstract

Tuberculosis (TB) remains a significant global health challenge. Miliary TB is a rare manifestation of TB that involves systemic lymphohematogenous dissemination of infection and presents diagnostic challenges due to its often asymptomatic or non-specific nature. This case report documents a rare occurrence of gastrointestinal (GI) bleeding secondary to miliary TB without pulmonary symptoms in an 81-year-old Filipino-American male living in the United States. Extensive imaging studies revealed a mass in the right colon with multiple bleeding vessels draped around it; it was not amendable to treatment with embolization and required right hemicolectomy with end ileostomy. The pathology report of the excised mass demonstrated miliary TB with necrotizing granulomas and granulomatous lymphadenopathy involving 23 lymph nodes. The patient was started on anti-tuberculosis medical management; however, the patient remained clinically unstable and expired on postoperative day 39. This case highlights the importance of the heightened clinical awareness required during times of globalization and in regions with dense immigrant populations. We aim to delineate the clinical understanding of gastrointestinal TB (GITB) and review possible indications for surgical management. We aim to help reduce diagnostic delay, therefore improving patient outcomes and limiting the spread of disease.

摘要

结核病(TB)仍然是一项重大的全球卫生挑战。粟粒性结核病是结核病的一种罕见表现形式,涉及感染的全身淋巴血行播散,由于其通常无症状或具有非特异性,因此在诊断方面存在挑战。本病例报告记录了一名居住在美国的81岁菲律宾裔美国男性,发生了罕见的粟粒性结核病继发胃肠道(GI)出血且无肺部症状的情况。广泛的影像学检查显示右结肠有一个肿块,周围有多处出血血管;该肿块无法通过栓塞治疗,需要进行右半结肠切除术并做末端回肠造口术。切除肿块的病理报告显示为粟粒性结核病,伴有坏死性肉芽肿和累及23个淋巴结 的肉芽肿性淋巴结病。患者开始接受抗结核药物治疗;然而,患者临床状况仍不稳定,术后第39天死亡。本病例突出了在全球化时代以及移民人口密集地区提高临床意识的重要性。我们旨在阐述对胃肠道结核病(GITB)的临床认识,并回顾手术治疗的可能指征。我们旨在帮助减少诊断延误,从而改善患者预后并限制疾病传播。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b66e/11056080/1b739c0a49d2/cureus-0016-00000057177-i01.jpg

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本文引用的文献

1
Disseminated Miliary and Intestinal Tuberculosis Mimicking Inflammatory Bowel Disease.
Cureus. 2023 Dec 5;15(12):e50002. doi: 10.7759/cureus.50002. eCollection 2023 Dec.
2
Barriers to tuberculosis care in the Philippines.
Lancet Respir Med. 2022 Jun;10(6):e55. doi: 10.1016/S2213-2600(22)00181-3.
3
Extrapulmonary tuberculosis.
Expert Rev Respir Med. 2021 Jul;15(7):931-948. doi: 10.1080/17476348.2021.1927718. Epub 2021 Jul 14.
4
Clinical Characteristics and Etiologies of Miliary Nodules in the US: A Single-Center Study.
Am J Med. 2019 Jun;132(6):767-769. doi: 10.1016/j.amjmed.2018.12.030. Epub 2019 Jan 16.
5
Atypical serious hematochezia and rare imaging feature in gastrointestinal tuberculosis.
Clin J Gastroenterol. 2019 Apr;12(2):182-188. doi: 10.1007/s12328-018-0910-0. Epub 2018 Sep 19.
6
Abdominal tuberculosis: Is there a role for surgery?
World J Gastrointest Surg. 2017 Aug 27;9(8):174-181. doi: 10.4240/wjgs.v9.i8.174.
7
Clinically unrecognized miliary tuberculosis: an autopsy study.
Ann Saudi Med. 2016 Jan-Feb;36(1):42-50. doi: 10.5144/0256-4947.2016.42.
8
Abdominal tuberculosis of the gastrointestinal tract: revisited.
World J Gastroenterol. 2014 Oct 28;20(40):14831-40. doi: 10.3748/wjg.v20.i40.14831.
9
Miliary tuberculosis: new insights into an old disease.
Lancet Infect Dis. 2005 Jul;5(7):415-30. doi: 10.1016/S1473-3099(05)70163-8.
10
Abdominal tuberculosis.
Indian J Med Res. 2004 Oct;120(4):305-15.

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