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一名有既往接触史的年轻男子意外罹患粟粒性肺结核

An Unexpected Encounter With Miliary Tuberculosis in a Young Man With a Remote Exposure History.

作者信息

Janardan Abhishek, Ayoub Malek, Khan Husna, Jha Pinky, Carter Valerie

机构信息

Internal Medicine, Medical College of Wisconsin, Milwaukee, USA.

Internal Medicine, Medical College of Wisconsin, Wauwatosa, USA.

出版信息

Cureus. 2022 May 29;14(5):e25454. doi: 10.7759/cureus.25454. eCollection 2022 May.

DOI:10.7759/cureus.25454
PMID:35774660
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9239527/
Abstract

Miliary tuberculosis (TB) represents a rare escalation of TB stemming from the hematogenous dissemination of Common extrapulmonary infection sites include the lymphatic system, musculoskeletal system, and central nervous system. The nonspecific motif of clinical symptoms involving joint pain, fever of unknown origin, and night sweats make the diagnosis of disseminated TB quite challenging. Long-term outcomes remain bleak. Untreated miliary TB is estimated to be fatal within one year. Here, we present a case of miliary TB in a 21-year-old male with a remote exposure history who was not immunocompromised.

摘要

粟粒性肺结核是由结核菌血行播散引起的一种罕见的严重肺结核。常见的肺外感染部位包括淋巴系统、肌肉骨骼系统和中枢神经系统。临床症状如关节疼痛、不明原因发热和盗汗等缺乏特异性,这使得播散性肺结核的诊断颇具挑战性。长期预后依然不容乐观。未经治疗的粟粒性肺结核估计在一年内会致命。在此,我们报告一例21岁男性粟粒性肺结核病例,该患者既往有接触史,但无免疫功能低下情况。

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An Unexpected Encounter With Miliary Tuberculosis in a Young Man With a Remote Exposure History.一名有既往接触史的年轻男子意外罹患粟粒性肺结核
Cureus. 2022 May 29;14(5):e25454. doi: 10.7759/cureus.25454. eCollection 2022 May.
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Miliary Tuberculosis粟粒性肺结核
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Diagnosis and management of miliary tuberculosis: current state and future perspectives.粟粒性肺结核的诊断与治疗:现状与未来展望。
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Disseminated tuberculosis in an immunocompetent woman from the Himalayan region of Nepal: A case report.尼泊尔喜马拉雅地区一名免疫功能正常女性的播散性肺结核:病例报告。
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本文引用的文献

1
Effectiveness of Preventive Therapy for Persons Exposed at Home to Drug-Resistant Tuberculosis, Karachi, Pakistan.在耐药结核病高发家庭中,对接触者进行预防治疗的效果,巴基斯坦卡拉奇。
Emerg Infect Dis. 2021 Mar;27(3):805-812. doi: 10.3201/eid2703.203916.
2
Miliary Tuberculosis Presenting with ARDS and Shock: A Case Report and Challenges in Current Management and Diagnosis.以急性呼吸窘迫综合征和休克为表现的粟粒性肺结核:一例报告及当前管理与诊断中的挑战
Case Rep Crit Care. 2017;2017:9287021. doi: 10.1155/2017/9287021. Epub 2017 Nov 28.
3
Challenges in the diagnosis & treatment of miliary tuberculosis.粟粒性肺结核的诊断与治疗难点。
Indian J Med Res. 2012 May;135(5):703-30.
4
Neurological complications of miliary tuberculosis.粟粒性肺结核的神经系统并发症
Clin Neurol Neurosurg. 2010 Apr;112(3):188-92. doi: 10.1016/j.clineuro.2009.11.013. Epub 2009 Dec 23.
5
Fever of unknown origin (FUO) caused by miliary tuberculosis: diagnostic significance of morning temperature spikes.粟粒性肺结核所致不明原因发热:晨峰热的诊断意义
Heart Lung. 2009 Jan-Feb;38(1):77-82. doi: 10.1016/j.hrtlng.2008.03.002. Epub 2008 Oct 1.
6
Miliary tuberculosis: new insights into an old disease.粟粒性肺结核:对一种古老疾病的新见解。
Lancet Infect Dis. 2005 Jul;5(7):415-30. doi: 10.1016/S1473-3099(05)70163-8.