Lahav M, Cadet J C
Albrecht Von Graefes Arch Klin Exp Ophthalmol. 1979 Aug;211(2):145-54. doi: 10.1007/BF00410138.
Clinical observation of corneal grafts often reveals subepithelial whitish opacities or membranes. To further understand the phenomenon, we undertook a histopathologic study of the changes in this region in failed human corneal grafts. Thinning and thickening of the epithelium, breaks in Bowman's membrane, and growth of subepithelial fibrous tissue were observed. Close association was found between the subepithelial fibrous growth, the breaks in Bowman's membrane, and stromal inflammation.
角膜移植的临床观察常常显示上皮下白色混浊或膜状物。为了进一步了解这一现象,我们对失败的人类角膜移植中该区域的变化进行了组织病理学研究。观察到上皮变薄和增厚、Bowman膜破裂以及上皮下纤维组织生长。发现上皮下纤维组织生长、Bowman膜破裂与基质炎症之间存在密切关联。