失败角膜移植术中的角膜后纤维膜

Retrocorneal fibrous membranes in failed corneal grafts.

作者信息

Kremer I, Rapuano C J, Cohen E J, Laibson P R, Eagle R C

机构信息

Cornea Service, Wills Eye Hospital, Jefferson Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania 19107.

出版信息

Am J Ophthalmol. 1993 Apr 15;115(4):478-83. doi: 10.1016/s0002-9394(14)74450-2.

DOI:10.1016/s0002-9394(14)74450-2

PMID:8470720

Abstract

Histopathologic slides from 170 failed grafts, excised between 1983 and 1990 were reviewed. The overall incidence of retrocorneal fibrous membrane was 54% (92 grafts). The incidence of diffuse (extensive) retrocorneal fibrous membrane was 17% (29 grafts) and that of focal (peripheral) retrocorneal fibrous membrane was 37% (63 grafts). A high correlation was found between the clinical presence of peripheral anterior synechiae or vitreous adherent to the wound and the finding of retrocorneal fibrous membrane in aphakic and pseudophakic failed corneal grafts. A high correlation was also found between tube-shunt operation and the presence of diffuse retrocorneal fibrous membrane. Sixteen of 63 (25%) regrafted failed grafts, that is second grafts, with focal retrocorneal fibrous membranes failed within 18 months following surgery. Thirteen of 29 (45%) regrafted failed grafts with diffuse retrocorneal fibrous membrane failed within the same period and 11 of these (85%) were associated with tube-shunt surgery.

摘要

回顾了1983年至1990年间切除的170例失败移植物的组织病理学切片。角膜后纤维膜的总体发生率为54%（92例移植物）。弥漫性（广泛性）角膜后纤维膜的发生率为17%（29例移植物），局灶性（周边性）角膜后纤维膜的发生率为37%（63例移植物）。在无晶状体和假晶状体失败角膜移植物中，周边前粘连或玻璃体粘连于伤口的临床存在与角膜后纤维膜的发现之间存在高度相关性。在引流管分流手术与弥漫性角膜后纤维膜的存在之间也发现了高度相关性。63例（25%）再次移植失败移植物（即第二次移植物）中有16例伴有局灶性角膜后纤维膜，在手术后18个月内失败。29例再次移植失败移植物中有13例（45%）伴有弥漫性角膜后纤维膜，在同一时期内失败，其中11例（85%）与引流管分流手术有关。