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[伴有急性骨筋膜室综合征的毒蛛咬伤:一例成功治愈的病例报告]

[Loxoscelism with acute compartment síndrome: A case report with successful conclusion].

作者信息

Sánchez-Perez Itzel Yoselin, Chávez-Ríos Yareni, Moreno-Hernández Sergio Gerardo, Velasco-Medina Andrea, Velázquez-Sámano Guillermo, Ramos-Martínez Espiridión

机构信息

Servicio de Alergia e Inmunología Clínica.

Servicio de Cirugía plástica Hospital General de México Dr. Eduardo Liceaga, Ciudad de México.

出版信息

Rev Alerg Mex. 2024 Feb 1;71(1):47-51. doi: 10.29262/ram.v71i1.1289.

Abstract

BACKGROUND

Loxoscelism is a toxic clinical condition caused by the bite of spiders of the genus , with wide distribution throughout the world.1 Phospholipase D is responsible for dermonecrosis, inflammation, platelet aggregation, hemolysis, alteration of vascular permeability, cytotoxicity, nephrotoxicity, acute renal failure, among other symptoms involved with this protein.

CASE REPORT

27-year-old male patient, who began with a sudden episode of intense pain in the right hand, in the metacarpus and metacarpophalangeal joints. On clinical examination, the upper extremity was noted to have increased volume, extensive edema, hyperemia, and increased local temperature; The lesion progressed to extensive necrosis. Fasciotomies were performed, from distal to proximal, and release of the second and third finger compartment through longitudinal radial and ulnar incisions. A skin autograft was placed, obtained from the anterior surface of the right thigh. Opioid analgesics, non-steroidal anti-inflammatory drugs, corticosteroids, and antibiotics were administered. The skin biopsy reported: inflammatory infiltrate with neutrophils, ulceration, and bacterial colonies. After 27 days he had a favorable evolution, so he was discharged to his home, with follow-up by staff from the Outpatient Service.

CONCLUSION

Cutaneous loxoscelism, as a cause of acute compartment syndrome of the hand, is rare, but should be considered in an area endemic for . Surgical decompression of the affected compartments represents a decisive factor in the treatment of patients.

摘要

背景

蜘蛛咬伤症是一种由 属蜘蛛叮咬引起的中毒性临床病症,在全球广泛分布。1 磷脂酶 D 会导致皮肤坏死、炎症、血小板聚集、溶血、血管通透性改变、细胞毒性、肾毒性、急性肾衰竭以及与该蛋白相关的其他症状。

病例报告

一名 27 岁男性患者,起初右手掌和掌指关节突然出现剧痛。临床检查发现上肢肿胀、广泛水肿、充血且局部温度升高;病变发展为广泛坏死。从远端到近端进行了筋膜切开术,并通过桡侧和尺侧纵行切口松解第二和第三指间隙。取自右大腿前表面的皮肤进行了自体移植。给予了阿片类镇痛药、非甾体抗炎药、皮质类固醇和抗生素。皮肤活检报告显示:有中性粒细胞炎性浸润、溃疡和细菌菌落。27 天后病情好转,遂出院回家,由门诊工作人员进行随访。

结论

皮肤蜘蛛咬伤症作为手部急性筋膜室综合征的病因较为罕见,但在 流行地区应予以考虑。对受影响的筋膜室进行手术减压是治疗患者的决定性因素。

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