光形态建成过程中组成型光形态建成1作用的分子基础。

The molecular basis of CONSTITUTIVE PHOTOMORPHOGENIC1 action during photomorphogenesis.

作者信息

Zhou Hua, Deng Xing Wang

机构信息

Key Laboratory of Molecular Design for Plant Cell Factory of Guangdong Higher Education Institutes, Department of Biology, Institute of Plant and Food Sciences, School of Life Sciences, Southern University of Science and Technology, Shenzhen 518055, China.

National Key Laboratory of Wheat Improvement, Peking University Institute of Advanced Agricultural Sciences, Shandong Laboratory of Advanced Agricultural Sciences at Weifang, Shandong 61000, China.

出版信息

J Exp Bot. 2025 Feb 7;76(3):664-676. doi: 10.1093/jxb/erae181.

DOI:10.1093/jxb/erae181

PMID:38683181

Abstract

CONSTITUTIVE PHOTOMORPHOGENIC1 (COP1), a repressor of seedling photomorphogenesis, is tightly controlled by light. In Arabidopsis, COP1 primarily acts as a part of large E3 ligase complexes and targets key light-signaling factors for ubiquitination and degradation. Upon light perception, the action of COP1 is precisely modulated by active photoreceptors. During seedling development, light plays a predominant role in modulating seedling morphogenesis, including inhibition of hypocotyl elongation, cotyledon opening and expansion, and chloroplast development. These visible morphological changes evidently result from networks of molecular action. In this review, we summarize current knowledge about the molecular role of COP1 in mediating light-controlled seedling development.

摘要

组成型光形态建成1（COP1）是幼苗光形态建成的抑制因子，受光的严格调控。在拟南芥中，COP1主要作为大型E3连接酶复合体的一部分发挥作用，并靶向关键的光信号因子进行泛素化和降解。在光感知时，COP1的作用受到活性光感受器的精确调节。在幼苗发育过程中，光在调节幼苗形态建成中起主要作用，包括抑制下胚轴伸长、子叶开放和扩展以及叶绿体发育。这些明显的形态变化显然是由分子作用网络导致的。在本综述中，我们总结了目前关于COP1在介导光控幼苗发育中的分子作用的知识。