Schultze B, Fietkau R, Schäfer E, Bassukas I
Ann N Y Acad Sci. 1985;459:278-92. doi: 10.1111/j.1749-6632.1985.tb20837.x.
The three studies discussed show that the response of experimental ascites and solid tumors, as well as of the host organism, to a cytotoxic drug can be studied quantitatively with cell kinetic methods. Knowledge of this kind is necessary in the attempt to improve the application of cytotoxic drugs in chemotherapy of tumors which up to now has been based mainly on pure empiricism.
所讨论的三项研究表明,利用细胞动力学方法可以定量研究实验性腹水和实体瘤以及宿主生物体对细胞毒性药物的反应。在试图改进细胞毒性药物在肿瘤化疗中的应用时,这类知识是必要的,因为到目前为止,肿瘤化疗主要基于纯粹的经验主义。