Klöcking H P
Arch Toxicol Suppl. 1985;8:142-7. doi: 10.1007/978-3-642-69928-3_20.
The normal haemostatic process depends on the normal function of and regular interaction between the vascular wall, the plasmatic coagulation system and the blood platelets. The consequences of interference of chemical compounds with haemostasis are bleeding tendency and bleeding, thrombophilia and thrombosis or disseminated intravascular coagulation. Examples will illustrate that chemicals interfering with haemostasis have different mechanisms and sites of action.
正常的止血过程依赖于血管壁、血浆凝血系统和血小板之间的正常功能及规律相互作用。化合物干扰止血的后果是出血倾向和出血、血栓形成倾向及血栓形成或弥散性血管内凝血。实例将说明干扰止血的化学物质具有不同的作用机制和作用部位。
