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男性有机勃起功能障碍与带状疱疹和带状疱疹后神经痛风险的关联。

Associations between organic erectile dysfunction and the risk of herpes zoster and postherpetic neuralgia in men.

机构信息

Department of Family Medicine, Antai Medical Care Corporation Antai Tian-Sheng Memorial Hospital, Pingtung, Taiwan.

Department of Chinese Medicine, Ditmanson Medical Foundation, Chia-Yi Christian Hospital, Chia-Yi, Taiwan.

出版信息

Aging Male. 2024 Dec;27(1):2346310. doi: 10.1080/13685538.2024.2346310. Epub 2024 Apr 29.

DOI:10.1080/13685538.2024.2346310
PMID:38685668
Abstract

BACKGROUND

Whether erectile dysfunction (ED) leads to considerable stress for affected men remains unclear? In this study, we investigated whether organic ED (OED) is associated with increased risks of herpes zoster (HZ) and postherpetic neuralgia (PHN).

METHODS

A representative subset of Taiwan's National Health Insurance Research Database was employed for this study. Enrollees with OED from the years 2000 to 2018 were selected. To ensure comparability between the case and control groups, we implemented 1:1 propensity score matching based on age, index year, comorbidities, and medications.

RESULTS

The case group included 20,808 patients with OED, while the control group consisted of 20,808 individuals without OED. The OED group exhibited a significantly elevated risk of HZ (adjusted hazard ratio [aHR] = 1.74) and PHN (aHR = 1.56) compared to the non-OED group.

CONCLUSIONS

Men experiencing OED seem to face elevated risks of HZ and PHN compared to those without OED. ED may serve as a warning sign for individuals at HZ risk.

摘要

背景

勃起功能障碍(ED)是否会给受影响的男性带来相当大的压力仍不清楚?在这项研究中,我们调查了器质性勃起功能障碍(OED)是否与带状疱疹(HZ)和带状疱疹后神经痛(PHN)的风险增加有关。

方法

本研究使用了台湾国家健康保险研究数据库的一个代表性子样本。从 2000 年至 2018 年选择了 OED 患者。为了确保病例组和对照组之间的可比性,我们根据年龄、索引年、合并症和药物进行了 1:1 的倾向评分匹配。

结果

病例组包括 20808 例 OED 患者,对照组包括 20808 例无 OED 患者。与非 OED 组相比,OED 组发生 HZ(调整后的危险比[aHR] = 1.74)和 PHN(aHR = 1.56)的风险显著升高。

结论

与无 OED 者相比,患有 OED 的男性似乎面临更高的 HZ 和 PHN 风险。ED 可能是 HZ 风险个体的一个警告信号。

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