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基于半监督神经网络的弹性模量分布重建

[Reconstruction of elasticity modulus distribution base on semi-supervised neural network].

作者信息

Zhang Xiao, Peng Bo, Wang Rui, Wei Xingyue, Luo Jianwen

机构信息

School of Computer Science and Software Engineering, Southwest Petroleum University, Chengdu 610500, P. R. China.

Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing 100084, P. R. China.

出版信息

Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2024 Apr 25;41(2):262-271. doi: 10.7507/1001-5515.202306008.

Abstract

Accurate reconstruction of tissue elasticity modulus distribution has always been an important challenge in ultrasound elastography. Considering that existing deep learning-based supervised reconstruction methods only use simulated displacement data with random noise in training, which cannot fully provide the complexity and diversity brought by ultrasound data, this study introduces the use of displacement data obtained by tracking ultrasound radio frequency signals (i.e., real displacement data) during training, employing a semi-supervised approach to enhance the prediction accuracy of the model. Experimental results indicate that in phantom experiments, the semi-supervised model augmented with real displacement data provides more accurate predictions, with mean absolute errors and mean relative errors both around 3%, while the corresponding data for the fully supervised model are around 5%. When processing real displacement data, the area of prediction error of semi-supervised model was less than that of fully supervised model. The findings of this study confirm the effectiveness and practicality of the proposed approach, providing new insights for the application of deep learning methods in the reconstruction of elastic distribution from ultrasound data.

摘要

在超声弹性成像中,准确重建组织弹性模量分布一直是一项重要挑战。鉴于现有的基于深度学习的监督重建方法在训练中仅使用带有随机噪声的模拟位移数据,无法充分体现超声数据所带来的复杂性和多样性,本研究引入在训练期间使用通过跟踪超声射频信号获得的位移数据(即真实位移数据),采用半监督方法来提高模型的预测准确性。实验结果表明,在体模实验中,用真实位移数据增强的半监督模型提供了更准确的预测,平均绝对误差和平均相对误差均在3%左右,而全监督模型的相应数据约为5%。在处理真实位移数据时,半监督模型的预测误差面积小于全监督模型。本研究结果证实了所提方法的有效性和实用性,为深度学习方法在从超声数据重建弹性分布中的应用提供了新的见解。

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Proc Natl Acad Sci U S A. 2021 Aug 3;118(31). doi: 10.1073/pnas.2102721118.
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Ultrasound Elastography: Review of Techniques and Clinical Applications.超声弹性成像:技术与临床应用综述
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Ultrasound elastography: principles and techniques.超声弹性成像:原理与技术。
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