Paillard J, Languillat N, Treuil C, Behar A, Atlan H, Baillet J
Ann Med Interne (Paris). 1979;130(6-7):349-53.
Muscle blood flow measurements are of physiological (and pathological) significance only during effort. For this reason, the authors used Xe 133, which has been known since 1964, to measure regional muscle blood flow after its injection into the muscle, to quantify results during effort (pedalling). Effort is controlled by two measurable parameters: the weight lifted by the pedal and the frequency of movements. Curves showing the reduction in intramuscular Xe 133 levels cannot be mathematically formulated. It is easy, however, to measure their areas and thus define a mean elimination time (Tm) between times T1 and T2, beginning and end of effort, corresponding to activities A1 and A2 such that: formula: (see text). Normal Tm value, measured in 58 normal subjects with variable frequencies and weights lifted is: Tm = 1.70 +/- 0.38 min. The values in 70 patients with arteritis were significantly longer and can be greater than 3.5 min. This objective test could be of value in quintifying the effects of so-called vasodilators, both in patients with arteritis and venous insufficiency.
肌肉血流量测量仅在用力过程中具有生理（及病理）意义。因此，作者使用自1964年起就已为人所知的氙133，在将其注入肌肉后测量局部肌肉血流量，以量化用力（蹬踏板）过程中的结果。用力由两个可测量参数控制：踏板举起的重量和运动频率。显示肌肉内氙133水平降低的曲线无法用数学公式表示。然而，测量它们的面积并由此定义用力开始时间T1和结束时间T2之间的平均消除时间（Tm）很容易，这对应于活动A1和A2，使得：公式：（见原文）。在58名频率和举起重量各异的正常受试者中测量的正常Tm值为：Tm = 1.70 +/- 0.38分钟。70名动脉炎患者的数值明显更长，可能大于3.5分钟。这项客观测试对于量化所谓血管扩张剂对动脉炎和静脉功能不全患者的影响可能具有价值。
