von Eiff A W, Gogolin E, Jacobs U, Neus H
J Hypertens Suppl. 1985 Dec;3(4):S89-91.
Since 1981 the 'Bonn Kinderstudie' has followed blood pressure (BP) development in children. In a subset of 63 healthy boys (aged 10-12 years at the beginning of the study) we examined whether cardiovascular reactivity predicts future BP development. At a 1-year interval BP and heart rate (HR) were measured during mental arithmetic and physical exercise. Ambulatory BP was assessed nine times per year. Among different reactivity scores HR reactivity to mental stress was the most stable variable. Only reactivity of systolic BP to mental stress was different between subjects with parental hypertension and subjects with a negative family history of hypertension. After 1 year high HR reactors developed about 7 mmHg higher ambulatory systolic BP levels than low HR reactors. It is concluded that besides genetic factors HR reactivity to mental stress might indicate the disposition for developing high BP.
自1981年以来，“波恩儿童研究”一直在跟踪儿童的血压发展情况。在63名健康男孩的子集中（研究开始时年龄为10至12岁），我们研究了心血管反应性是否能预测未来的血压发展。每隔1年，在进行心算和体育锻炼时测量血压和心率（HR）。每年评估9次动态血压。在不同的反应性评分中，心率对精神压力的反应性是最稳定的变量。只有收缩压对精神压力的反应性在有父母高血压的受试者和有高血压阴性家族史的受试者之间有所不同。1年后，高心率反应者的动态收缩压水平比低心率反应者高约7 mmHg。得出的结论是，除了遗传因素外，心率对精神压力的反应性可能表明患高血压的倾向。
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