Department of Obstetrics, Gynecology, and Reproductive Sciences, Division of Maternal-Fetal Medicine, University of California, La Jolla, California.
Clin Obstet Gynecol. 2024 Jun 1;67(2):399-410. doi: 10.1097/GRF.0000000000000865. Epub 2024 Apr 29.
The Antenatal Late Preterm Steroids (ALPS) trial was designed to address respiratory morbidity common in infants born late preterm. The study was published in April, 2016 and, shortly thereafter, changed clinical practice in obstetrics in the United States. The following chapter describes the ALPS trial study design in detail, including the background leading to the trial, the study outcomes, and the initial findings of the long-term follow-up study. The ALPS story would not be complete without Elizabeth Thom, PhD, who died before her time. Her brilliance largely contributed to the design of the ALPS trial.
产前晚期早产儿类固醇（ALPS）试验旨在解决晚期早产儿常见的呼吸发病率问题。该研究于 2016 年 4 月发表，此后不久，改变了美国产科的临床实践。以下章节详细描述了 ALPS 试验的研究设计，包括导致该试验的背景、研究结果以及长期随访研究的初步发现。如果没有伊丽莎白·汤姆博士（Elizabeth Thom, PhD），ALPS 的故事就不完整。她的才华主要为 ALPS 试验的设计做出了贡献。
