Department of Otorhinolaryngology and Head and Neck Surgery, Guangzhou Red Cross Hospital, China.
Department of Otorhinolaryngology and Head and Neck Surgery, Guangzhou Red Cross Hospital, China.
Am J Otolaryngol. 2024 Jul-Aug;45(4):104301. doi: 10.1016/j.amjoto.2024.104301. Epub 2024 Apr 16.
This study aimed to compare the efficacy of balloon Eustachian tuboplasty (BET) plus tympanostomy tube insertion (TTI) and simple TTI for postirradiation otitis media with effusion (OME) in patients with nasopharyngeal carcinoma.
This study included 36 patients (51 ears) with OME after the first radiotherapy course for nasopharyngeal carcinoma and categorized them into the BET + TTI and simple TTI groups. Effective rates, pure tone hearing threshold, Eustachian tube function score, and complication incidences were compared.
The effective rates of the BET+TTI and TTI groups were 93.75 % and 75 %, respectively, with no statistically significant difference (P = 0.29). The pure tone hearing threshold examination at 9 months postoperatively revealed significantly lower mean air-pure tone and air-bone gap in both the BET + TTI and TTI groups than preoperatively. Eustachian Tube Dysfunction Questionnaire-7 (ETDQ-7) scores at every postoperative visit were significantly higher than preoperative scores in the two groups (all P < 0.05); ETDQ-7 score reduction in the BET + TTI group at 3, 9, and 12 months postoperatively was significantly higher than that in the TTI group. Otorrhea and recurrence both occurred in the BET+TTI and TTI groups, but the BET+TTI group demonstrated a lower incidence.
BET + TTI is an effective treatment method for postirradiation OME.
本研究旨在比较球囊咽鼓管成形术(BET)联合鼓膜置管术(TTI)与单纯 TTI 治疗鼻咽癌放疗后分泌性中耳炎(OME)的疗效。
本研究纳入了 36 例(51 耳)接受首次鼻咽癌放疗后出现 OME 的患者,将其分为 BET+TTI 组和单纯 TTI 组。比较两组的有效率、纯音听阈、咽鼓管功能评分和并发症发生率。
BET+TTI 组和 TTI 组的有效率分别为 93.75%和 75%,差异无统计学意义(P=0.29)。术后 9 个月的纯音听阈检查显示,BET+TTI 组和 TTI 组的平均气导纯音和气骨导差均明显低于术前。两组患者在术后每次随访时的咽鼓管功能障碍问卷-7(ETDQ-7)评分均明显高于术前(均 P<0.05);BET+TTI 组在术后 3、9 和 12 个月时 ETDQ-7 评分的降低幅度明显高于 TTI 组。BET+TTI 组和 TTI 组均出现耳漏和复发,但 BET+TTI 组的发生率较低。
BET+TTI 是治疗放疗后 OME 的有效方法。