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How to identify early complications in patients undergoing distal gastrectomy?

作者信息

Tropeano Giuseppe, Chiarello Maria Michela, Fico Valeria, Brisinda Giuseppe

机构信息

Emergency Surgery and Trauma Center, Fondazione Policlinico Universitario A Gemelli IRCCS, Rome 00168, Italy.

Department of Surgery, Azienda Sanitaria Provinciale di Cosenza, Cosenza 87100, Italy.

出版信息

World J Gastrointest Surg. 2024 Apr 27;16(4):974-981. doi: 10.4240/wjgs.v16.i4.974.


DOI:10.4240/wjgs.v16.i4.974
PMID:38690038
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11056664/
Abstract

In this editorial we comment on the article by Zhang published in a recent issue of the W. Gastrectomy with appropriate lymph node dissection is still standard curative treatment in locally advanced gastric cancer. Several studies point out that gastric cancer surgery is a complex procedure that leads to a high risk of morbidity and mortality. Many factors can contribute to the onset of complications with consequent effects on prognosis and increased mortality. The complications can be divided in complications related to anastomosis, to motility and to surgical site infection. The study presented by Zhang B represent an interesting analysis on the possibility to prevent postoperative morbidity. The study was performed on 131 patients with distal gastric cancer who underwent gastrectomy with D2 lymph node dissection. Of these patients, 16% developed early postoperative complications. The univariate analysis showed that prealbumin level, hypertension, diabetes, history of abdominal surgery, R0 resection, and blood transfusion were factors influencing early postoperative complications after distal gastrectomy. Moreover, the inclusion of the above significant variables in the logistic regression analysis revealed that hypertension, diabetes, a history of abdominal surgery, and blood transfusion were independent predictors of postoperative complications. In conclusion, preoperative and intraoperative factors can be used to establish an early postoperative nomogram model. The results of the study presented by Zhang suggest that the prediction model can be used to guide the detection of postoperative complications and has clinical reference value.

摘要

相似文献

[1]
How to identify early complications in patients undergoing distal gastrectomy?

World J Gastrointest Surg. 2024-4-27

[2]
[Early postoperative complications and risk factors in laparoscopic D2 radical gastrectomy for gastric cancer].

Zhonghua Wei Chang Wai Ke Za Zhi. 2019-8-25

[3]
[Safety and efficacy of adjuvant chemotherapy with oxaliplatin and S-1 for patients with locally advanced gastric cancer after D2 lymph nodes dissection].

Zhonghua Wei Chang Wai Ke Za Zhi. 2021-2-25

[4]
[Clinical value of superior mesenteric vein (No.14v) lymph node dissection in D2 gastrectomy for locally advanced distal gastric cancer].

Zhonghua Wei Chang Wai Ke Za Zhi. 2018-10-25

[5]
[Safety and efficacy of laparoscopic surgery in locally advanced gastric cancer patients with neoadjuvant chemotherapy combined with immunotherapy].

Zhonghua Wei Chang Wai Ke Za Zhi. 2023-1-25

[6]
[Establishment and validation of a predictive nomogram model for advanced gastric cancer with perineural invasion].

Zhonghua Wei Chang Wai Ke Za Zhi. 2020-11-25

[7]
Impact of Abdominal Shape on Short-Term Surgical Outcome of Laparoscopy-Assisted Distal Gastrectomy for Gastric Cancer.

J Gastrointest Surg. 2016-6

[8]
An Optimal Surgical Approach for Suprapancreatic Area Dissection in Laparoscopic D2 Gastrectomy with Complete Mesogastric Excision.

J Gastrointest Surg. 2020-4

[9]
Postoperative mortality and morbidity after D2 lymphadenectomy for gastric cancer: A retrospective cohort study.

World J Gastroenterol. 2022-1-21

[10]
Prospective randomized controlled trial to compare laparoscopic distal gastrectomy (D2 lymphadenectomy plus complete mesogastrium excision, D2 + CME) with conventional D2 lymphadenectomy for locally advanced gastric adenocarcinoma: study protocol for a randomized controlled trial.

Trials. 2018-8-9

本文引用的文献

[1]
Nomogram for predicting early complications after distal gastrectomy.

World J Gastrointest Surg. 2023-11-27

[2]
Early postoperative CRP predicts major complications following cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC).

Pleura Peritoneum. 2023-6-2

[3]
Pattern of Distribution of Lymph Node Metastases in Individual Stations in Middle and Lower Gastric Carcinoma.

Cancers (Basel). 2023-4-4

[4]
Optimal Predictors of Postoperative Complications After Gastrectomy: Results from the Procalcitonin and C-reactive Protein for the Early Diagnosis of Anastomotic Leakage in Esophagogastric Surgery (PEDALES) Study.

J Gastrointest Surg. 2023-3

[5]
Early detection of anastomotic leak with C-reactive protein increases the chances of anastomotic salvage.

Colorectal Dis. 2023-4

[6]
Global burden of gastric cancer in adolescents and young adults: estimates from GLOBOCAN 2020.

Public Health. 2022-9

[7]
Early gastric cancer: A challenge in Western countries.

World J Gastroenterol. 2022-2-21

[8]
Postoperative mortality and morbidity after D2 lymphadenectomy for gastric cancer: A retrospective cohort study.

World J Gastroenterol. 2022-1-21

[9]
Anastomotic leakage in colorectal cancer surgery.

Surg Oncol. 2022-3

[10]
Hospital volume following major surgery for gastric cancer determines in-hospital mortality rate and failure to rescue: a nation-wide study based on German billing data (2009-2017).

Gastric Cancer. 2021-7

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