CCR5-edited CD4+ T cells augment HIV-specific immunity to enable post-rebound control of HIV replication.
作者信息
Tebas Pablo, Jadlowsky Julie K, Shaw Pamela A, Tian Lifeng, Esparza Erin, Brennan Andrea L, Kim Sukyung, Naing Soe Yu, Richardson Max W, Vogel Ashley N, Maldini Colby R, Kong Hong, Liu Xiaojun, Lacey Simon F, Bauer Anya M, Mampe Felicity, Richman Lee P, Lee Gary, Ando Dale, Levine Bruce L, Porter David L, Zhao Yangbing, Siegel Don L, Bar Katharine J, June Carl H, Riley James L
出版信息
J Clin Invest. 2024 May 1;134(9):e181576. doi: 10.1172/JCI181576.
Abstract
摘要
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CCR5-edited CD4+ T cells augment HIV-specific immunity to enable post-rebound control of HIV replication.经CCR5编辑的CD4+ T细胞增强HIV特异性免疫，以实现HIV复制反弹后的控制。
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