Department of Internal Medicine, University of Colorado Hospital.
University of Colorado School of Medicine, University of Colorado.
Curr Opin Crit Care. 2024 Jun 1;30(3):260-267. doi: 10.1097/MCC.0000000000001155. Epub 2024 Mar 28.
Venous pressure is an often-unrecognized cause of patient morbidity. However, bedside assessment of PV is challenging. We review the clinical significance of venous pressure measurement, existing techniques, and introduce the Venous Excess Ultrasound (VExUS) Score as a novel approach using doppler ultrasound to assess venous pressure.
Studies show clear associations between elevated venous pressure and adverse outcomes in critically ill patients. Current venous pressure measurement techniques include physical examination, right heart catheterization (RHC), two-dimensional ultrasound, and a variety of labor-intensive research-focused physiological maneuvers. Each of these techniques have specific shortcomings, limiting their clinical utility. To address these gaps, Beaubien-Souligny et al. introduced the VExUS Score, a novel doppler ultrasound-based method that integrates IVC diameter with doppler measurements of the hepatic, portal, and renal veins to generate a venous congestion assesment. Studies show strong correlations between VExUS score and RHC measurements, and well as an association between VExUS score and improvement in cardiorenal acute kidney injury, diuretic response, and fluid status shifts. However, studies in noncardiac populations have been small, heterogenous, and inconclusive.
Early studies evaluating the use of doppler ultrasound to assess venous congestion show promise, but further research is needed in diverse patient populations and clinical settings.
静脉压是导致患者发病率的一个经常被忽视的原因。然而,床边评估中心静脉压具有挑战性。我们回顾了静脉压测量的临床意义、现有的技术,并介绍了静脉过度超声(VExUS)评分,这是一种使用多普勒超声评估静脉压的新方法。
研究表明,危重患者的静脉压升高与不良预后之间存在明确的关联。目前的静脉压测量技术包括体格检查、右心导管检查(RHC)、二维超声以及各种需要耗费大量精力的研究导向的生理操作。这些技术各有其特定的缺点,限制了其临床应用。为了解决这些差距,Beaubien-Souligny 等人引入了 VExUS 评分,这是一种新的基于多普勒超声的方法,该方法将 IVC 直径与肝静脉、门静脉和肾静脉的多普勒测量相结合,以生成静脉充血评估。研究表明,VExUS 评分与 RHC 测量之间存在很强的相关性,以及与心脏肾急性肾损伤、利尿剂反应和液体状态变化的改善之间存在相关性。然而,在非心脏人群中的研究规模较小、异质性较大且结论不一致。
早期评估使用多普勒超声评估静脉充血的研究显示出前景,但在不同的患者人群和临床环境中还需要进一步的研究。