Department of Psychiatry, University of Connecticut, Farmington, CT; Medical Director, Hartford Behavioral Health, Hartford, CT.
Department of Psychiatry, University of Connecticut, Farmington, CT; Farrell Treatment Center, New Britain, CT.
Cleve Clin J Med. 2024 May 1;91(5):293-299. doi: 10.3949/ccjm.91a.23061.
Benzodiazepines are widely used but can cause considerable harm, including sedation, addiction, falls, fractures, and cognitive impairment, especially with long-term use and in elderly patients. The authors propose a public health approach to reduce the potential for harm when using benzodiazepines to treat insomnia. Primary prevention involves judicious patient selection and patient education. Secondary prevention requires keeping the duration of use as short as possible according to guidelines. Tertiary prevention, for patients who have been taking a benzodiazepine for a long time, uses shared decision-making to introduce a gradual and carefully monitored taper.
苯二氮䓬类药物被广泛使用,但可能会造成相当大的危害,包括镇静、成瘾、跌倒、骨折和认知障碍,尤其是长期使用和老年患者。作者提出了一种公共卫生方法,以减少在使用苯二氮䓬类药物治疗失眠时的潜在危害。一级预防包括谨慎选择患者和患者教育。二级预防需要根据指南尽可能缩短使用时间。对于长期使用苯二氮䓬类药物的患者,三级预防采用共同决策,引入逐渐和仔细监测的减量。