Department of Pathology, Icahn School of Medicine at Mount Sinai, One Gustave Levy Place, Annenberg 15-76, New York, NY 10029, USA.
Surg Pathol Clin. 2024 Jun;17(2):215-225. doi: 10.1016/j.path.2023.11.007. Epub 2023 Dec 20.
Interstitial lung abnormalities (ILA) is a radiographic term, which has recently undergone clarification of definition with creation of 3 subtypes. ILA is defined as incidental identification of computed tomography abnormalities in a patient who is not suspected of having an interstitial lung disease (ILD). A subset of ILA may progress to clinically significant ILD and is associated with morbidities not related to progression such as an increased incidence of sepsis-related acute respiratory distress syndrome (ARDS). ILA has been associated with an increased incidence of treatment-related complications in patients with lung cancer. Information on corresponding histology is limited; knowledge gaps exist concerning optimal patient management.
间质性肺异常(ILA)是一个放射学术语,最近对其定义进行了澄清,分为 3 个亚型。ILA 定义为在疑似患有间质性肺疾病(ILD)的患者中偶然发现的计算机断层扫描异常。ILA 的一部分可能进展为临床显著的ILD,并与与进展无关的发病率相关,例如败血症相关的急性呼吸窘迫综合征(ARDS)的发生率增加。ILA 与肺癌患者治疗相关并发症的发生率增加有关。关于相应组织病理学的信息有限;在最佳患者管理方面存在知识空白。