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慢性溴中毒合并范科尼综合征

Chronic Bromine Intoxication Complicated with Fanconi Syndrome.

作者信息

Makio Yusuke, Harada Taku, Yamasato Kazushi, Nakanishi Toshiyuki, Nakai Mori

机构信息

Department of General Medicine, Nerima Hikarigaoka Hospital, Japan.

Department of Diagnostic and Generalist Medicine, Dokkyo Medical University Hospital, Japan.

出版信息

Intern Med. 2024 Dec 15;63(24):3395-3399. doi: 10.2169/internalmedicine.3128-23. Epub 2024 May 2.

DOI:10.2169/internalmedicine.3128-23
PMID:38692916
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11729184/
Abstract

In this report, we describe a unique case of an 80-year-old woman who developed chronic bromine poisoning due to the prolonged ingestion of over-the-counter (OTC) medication containing bromovalerylurea (BVU), thus leading to the onset of drug-induced partial Fanconi syndrome and resultant osteomalacia. The patient's condition improved following the cessation of bromide intake. This case highlights the potential risks of chronic BVU exposure and the importance of caution regarding the use of OTC medications containing BVU.

摘要

在本报告中，我们描述了一例独特的病例，一名80岁女性因长期摄入含溴戊酰脲（BVU）的非处方药而发生慢性溴中毒，进而引发药物性部分范科尼综合征并导致骨软化症。停止摄入溴化物后，患者的病情有所改善。该病例凸显了长期接触BVU的潜在风险以及谨慎使用含BVU非处方药的重要性。

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