Department of Orthopaedic Surgery and Rehabilitation Medicine, The State University of New York Downstate Health Sciences University, Brooklyn, NY, USA.
Department of Orthopaedic Surgery, Chang Gung Memorial Hospital, Keelung Branch, Bone and Joint Research Center and Chang Gung University, F7, No 222 Mai-King Road, Keelung, Taiwan.
Eur J Orthop Surg Traumatol. 2024 Jul;34(5):2557-2564. doi: 10.1007/s00590-024-03955-1. Epub 2024 May 1.
This study investigates baseline patient demographics and predictors of vascular injury, blood transfusion, and compartment syndrome in patients with orthopaedic fractures secondary to GSWs at two high-volume Level I trauma centres.
A retrospective chart review of all GSW-related trauma patients at two Level I trauma centres between July 2019 and September 2021 was conducted. Chi-squared and two-tailed independent t tests were used for data analysis, and logistic regression with odds ratios (OR) determined predictors of primary outcomes.
Among 478 GSW patients, 94 (19.7%) sustained 130 orthopaedic fractures, most commonly at the lower extremity (77.7%). Orthopaedic fracture patients showed significantly higher rates of vascular injury (29.8 vs. 4.7%, p < 0.001), transfusion (27.7 vs. 12.8%, p = 0.006), and compartment syndrome (3.2 vs. 0.3%, p = 0.011) compared to non-orthopaedic injury patients. Univariable analysis identified ankle (OR = 47.50, p < 0.001) and hip/femur fractures (OR = 5.31, p < 0.001) as predictors of vascular injury. Multivariable logistic regression revealed lower extremity vascular injury (OR = 54.69, p = 0.006) and anatomic fracture sites of the humerus (OR = 15.17, p = 0.008), clavicle/scapula (OR = 11.30, p = 0.009), and acetabulum/pelvis (OR = 7.17, p = 0.025) as predictors of blood transfusion. Univariable analysis showed lower extremity vascular injury (OR = 30.14, p = 0.007) as a predictor of compartment syndrome.
These findings underscore the importance of diagnosing and managing vascular injuries and compartment syndrome in GSW-related orthopaedic fractures, emphasizing the necessity for targeted transfusion strategies in such cases.
本研究旨在调查两家高容量一级创伤中心收治的因枪伤导致骨科骨折的患者中,基线患者人口统计学特征以及血管损伤、输血和间隔综合征的预测因素。
对 2019 年 7 月至 2021 年 9 月期间在两家一级创伤中心收治的所有枪伤相关创伤患者进行回顾性图表审查。使用卡方检验和双尾独立 t 检验进行数据分析,采用逻辑回归分析确定主要结局的预测因素。
在 478 例枪伤患者中,有 94 例(19.7%)发生 130 处骨科骨折,最常见于下肢(77.7%)。与非骨科损伤患者相比,骨科骨折患者的血管损伤(29.8%比 4.7%,p<0.001)、输血(27.7%比 12.8%,p=0.006)和间隔综合征(3.2%比 0.3%,p=0.011)发生率明显更高。单变量分析确定踝关节(OR=47.50,p<0.001)和髋/股骨骨折(OR=5.31,p<0.001)为血管损伤的预测因素。多变量逻辑回归显示下肢血管损伤(OR=54.69,p=0.006)和肱骨(OR=15.17,p=0.008)、锁骨/肩胛骨(OR=11.30,p=0.009)和髋臼/骨盆(OR=7.17,p=0.025)解剖骨折部位为输血的预测因素。单变量分析显示下肢血管损伤(OR=30.14,p=0.007)是间隔综合征的预测因素。
这些发现强调了在枪伤相关骨科骨折中诊断和处理血管损伤和间隔综合征的重要性,强调了在这种情况下需要制定针对性的输血策略。