Brown M A, Mullins R, Stokes G S, Györy A Z
Aust N Z J Med. 1985 Dec;15(6):751-4.
A 24 year old man developed partial central diabetes insipidus with impaired thirst and an elevated osmotic threshold to the release of arginine vasopressin (AVP). Plasma AVP was present in inappropriately small concentrations despite severe hyperosmolality. In addition, marked hypertension accompanied this disorder and all abnormalities, including the hypertension, responded to 1-desamino-8-D-arginine vasopressin therapy. Several lines of evidence suggest this disorder may be a disturbance of hypothalamic function.
一名24岁男性出现部分性中枢性尿崩症，伴有口渴受损以及精氨酸加压素（AVP）释放的渗透阈值升高。尽管存在严重高渗血症，但血浆AVP浓度却异常低。此外，该疾病伴有明显高血压，所有异常情况，包括高血压，对1-去氨基-8-D-精氨酸加压素治疗均有反应。多项证据表明，这种疾病可能是下丘脑功能紊乱。
