Abramson M, Pfueller S, Sheridan W
Aust N Z J Med. 1985 Dec;15(6):763-6.
We report two cases of purpura characterised by severe immune thrombocytopenia which appeared one to two weeks after blood transfusion during elective surgery. Both patients had antibodies to the platelet P1A1 antigen and displayed high levels of platelet-bindable IgG and IgM in their serum; they were treated with glucocorticoids and recovered after four weeks. One case relapsed following a further transfusion of packed red cells. Theories of pathogenesis, methods of diagnosis, and alternative forms of therapy are reviewed.
我们报告了两例紫癜病例，其特征为严重免疫性血小板减少，发生在择期手术输血后一至两周。两名患者均有针对血小板P1A1抗原的抗体，血清中血小板可结合的IgG和IgM水平较高；他们接受了糖皮质激素治疗，四周后康复。其中一例在再次输注浓缩红细胞后复发。本文回顾了发病机制理论、诊断方法及替代治疗形式。
