Alsharif Arwa T, Alanazi Omar I, Alqarni Rayan A, Alahmadi Hawazen O, Alassiri Lamis A, Alamri Shahad A, Khalifa Razan M, Alshehab Eman A, Alzahrani Rahmah B, Al Wahbi Abdullah
Department of Medicine, Batterjee Medical College, Jeddah, SAU.
Department of Medicine, King Saud Bin Abdulaziz University for Health Sciences, Riyadh, SAU.
Cureus. 2024 Apr 1;16(4):e57407. doi: 10.7759/cureus.57407. eCollection 2024 Apr.
Venous ulcers are open wounds commonly associated with chronic venous insufficiency. Each patient's healing process is unique, and factors like nutrition and compression therapy can affect it. Compression therapy and optimal nutritional status can assist in improving venous blood circulation, decreasing swelling, and promoting wound healing. This in-depth review looks at all the recent research on how nutrition and compression therapy can help heal venous ulcers, aiming to develop evidence-based guidelines for improving treatment outcomes. The systematic review, registered in the International Prospective Register of Systematic Reviews (PROSPERO) and following Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) principles, conducted an extensive electronic search in databases such as PubMed, MEDLINE, Cochrane, Web of Science, and Scopus. Using Medical Subject Headings (MeSH) terms and different types of studies, the search method focused on studies that directly looked at how nutrition and compression therapy affected the healing of venous ulcers. After deduplicating and screening publications, a collaborative full-text review was conducted to determine their inclusion. As a result, several research studies were chosen for the qualitative synthesis. The authors created a data extraction form to document important variables such as demographics, therapy specifics, and wound features. Several studies on patients with venous ulcers have shown that consuming basic nutrients can improve wound healing. Treatment results differed depending on the types of compression and pressure intensity. Although minimal data indicates the possible benefits of two-layer therapy, a definitive comparison is still uncertain. Further clinical studies are necessary to investigate a wider range of dietary factors and to evaluate different treatments in similar situations.
静脉性溃疡是通常与慢性静脉功能不全相关的开放性伤口。每位患者的愈合过程都是独特的，营养和加压治疗等因素会对其产生影响。加压治疗和最佳营养状况有助于改善静脉血液循环、减轻肿胀并促进伤口愈合。这篇深入综述审视了关于营养和加压治疗如何帮助治愈静脉性溃疡的所有最新研究，旨在制定基于证据的指南以改善治疗效果。该系统综述已在国际系统评价前瞻性注册库（PROSPERO）注册，并遵循系统评价和Meta分析的首选报告项目（PRISMA）原则，在PubMed、MEDLINE、Cochrane、科学网和Scopus等数据库中进行了广泛的电子检索。使用医学主题词（MeSH）术语和不同类型的研究，检索方法聚焦于直接研究营养和加压治疗如何影响静脉性溃疡愈合的研究。在对出版物进行去重和筛选后，进行了协作式全文审查以确定其是否纳入。结果，选择了几项研究进行定性综合分析。作者创建了一个数据提取表来记录重要变量，如人口统计学、治疗细节和伤口特征。几项针对静脉性溃疡患者的研究表明，摄入基本营养素可改善伤口愈合。治疗结果因加压类型和压力强度而异。尽管极少数据表明两层疗法可能存在益处，但仍无法进行明确比较。有必要开展进一步的临床研究，以调查更广泛的饮食因素，并在类似情况下评估不同的治疗方法。
