大脑中高乳酸水平会导致脑电图出现局灶性慢波。
High lactic acid levels in the brain contribute to the generation of focal slowing on the electroencephalogram.
作者信息
Chegodaev Dmitry Alexandrovich, Pavlova Polina Alekseevna
机构信息
Laboratory for Brain and Neurocognitive Development, Ural Institute of Humanities, Ural Federal University named after the First President of Russia B. N. Yeltsin, Yekaterinburg, Russia.
'Science Center for Cognitive Research, Sirius University of Science and Technology, Sirius, Russia.
出版信息
Front Neurol. 2024 Apr 17;15:1393274. doi: 10.3389/fneur.2024.1393274. eCollection 2024.
Focal slowing on the EEG is often associated with structural pathology of the brain. Despite the clinical significance of focal slowing, the actual electrochemical mechanisms underlying this EEG phenomenon are still poorly understood. This paper briefly reviews the role of lactate in the pathogenesis of brain disorders that are primarily related to focal EEG slowing. An attempt is made to trace the hypothetical link between this EEG pattern and focal cerebral tissue lactacidosis.
脑电图上的局灶性慢波常与脑部结构病变相关。尽管局灶性慢波具有临床意义，但其背后实际的电化学机制仍未得到充分理解。本文简要回顾了乳酸在主要与脑电图局灶性慢波相关的脑部疾病发病机制中的作用。试图探寻这种脑电图模式与局灶性脑组织乳酸性酸中毒之间的假设联系。
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