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Serum Response Factor Overexpression, a Double Trouble that May Underlie Airway Hyperresponsiveness in Asthma.

作者信息

Seow Chun Y

机构信息

Department of Pathology and Laboratory Medicine University of British Columbia Vancouver, British Columbia, Canada.

UBC Centre for Heart Lung Innovation St. Paul's Hospital-Providence Health Care Vancouver, British Columbia, Canada.

出版信息

Am J Respir Cell Mol Biol. 2024 Aug;71(2):141-142. doi: 10.1165/rcmb.2024-0168ED.

DOI:10.1165/rcmb.2024-0168ED
PMID:38696286
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11299080/
Abstract
摘要

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Serum Response Factor Overexpression, a Double Trouble that May Underlie Airway Hyperresponsiveness in Asthma.血清反应因子过表达：哮喘气道高反应性潜在的双重麻烦
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本文引用的文献

1
Serum Response Factor Expression in Excess Permits a Dual Contractile-Proliferative Phenotype of Airway Smooth Muscle.血清反应因子表达过度可使气道平滑肌呈现双重收缩-增殖表型。
Am J Respir Cell Mol Biol. 2024 Aug;71(2):182-194. doi: 10.1165/rcmb.2024-0081OC.
2
Rho-Kinase Inhibition of Active Force and Passive Tension in Airway Smooth Muscle: A Strategy for Treating Airway Hyperresponsiveness in Asthma.Rho激酶对气道平滑肌主动力和被动张力的抑制作用：一种治疗哮喘气道高反应性的策略。
Biology (Basel). 2024 Feb 11;13(2):115. doi: 10.3390/biology13020115.
3
Intrapulmonary airway smooth muscle is hyperreactive with a distinct proteome in asthma.在哮喘中，肺内气道平滑肌具有高反应性且拥有独特的蛋白质组。
Eur Respir J. 2020 Jul 2;56(1). doi: 10.1183/13993003.02178-2019. Print 2020 Jul.
4
Upregulation of smooth muscle Rho-kinase protein expression in human asthma.人类哮喘中平滑肌 Rho 激酶蛋白表达上调。
Eur Respir J. 2020 Mar 5;55(3). doi: 10.1183/13993003.01785-2019. Print 2020 Mar.
5
Airway smooth muscle hypertrophy and hyperplasia in asthma.哮喘中的气道平滑肌肥大和增生。
Am J Respir Crit Care Med. 2012 May 15;185(10):1058-64. doi: 10.1164/rccm.201110-1849OC. Epub 2012 Mar 8.
6
Myocardin and ternary complex factors compete for SRF to control smooth muscle gene expression.心肌素与三元复合因子竞争血清反应因子，以控制平滑肌基因表达。
Nature. 2004 Mar 11;428(6979):185-9. doi: 10.1038/nature02382.
7
Molecular mechanisms of phenotypic plasticity in smooth muscle cells.平滑肌细胞表型可塑性的分子机制
J Appl Physiol (1985). 2001 Jan;90(1):358-68. doi: 10.1152/jappl.2001.90.1.358.
8
Potent bronchoprotective effect of deep inspiration and its absence in asthma.深呼吸的强效支气管保护作用及其在哮喘中的缺失。
J Appl Physiol (1985). 2000 Aug;89(2):711-20. doi: 10.1152/jappl.2000.89.2.711.
9
Functional significance of increased airway smooth muscle in asthma and COPD.哮喘和慢性阻塞性肺疾病中气道平滑肌增加的功能意义。
J Appl Physiol (1985). 1993 Jun;74(6):2771-81. doi: 10.1152/jappl.1993.74.6.2771.
10
Regulation of bronchomotor tone by lung inflation in asthmatic and nonasthmatic subjects.哮喘患者和非哮喘患者中肺膨胀对支气管运动张力的调节
J Appl Physiol Respir Environ Exerc Physiol. 1981 May;50(5):1079-86. doi: 10.1152/jappl.1981.50.5.1079.