Serum Response Factor Overexpression, a Double Trouble that May Underlie Airway Hyperresponsiveness in Asthma.
作者信息
Seow Chun Y
机构信息
Department of Pathology and Laboratory Medicine University of British Columbia Vancouver, British Columbia, Canada.
UBC Centre for Heart Lung Innovation St. Paul's Hospital-Providence Health Care Vancouver, British Columbia, Canada.
出版信息
Am J Respir Cell Mol Biol. 2024 Aug;71(2):141-142. doi: 10.1165/rcmb.2024-0168ED.
Abstract
摘要
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Serum Response Factor Overexpression, a Double Trouble that May Underlie Airway Hyperresponsiveness in Asthma.血清反应因子过表达：哮喘气道高反应性潜在的双重麻烦
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本文引用的文献
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Serum Response Factor Expression in Excess Permits a Dual Contractile-Proliferative Phenotype of Airway Smooth Muscle.血清反应因子表达过度可使气道平滑肌呈现双重收缩-增殖表型。
Am J Respir Cell Mol Biol. 2024 Aug;71(2):182-194. doi: 10.1165/rcmb.2024-0081OC.
2
Rho-Kinase Inhibition of Active Force and Passive Tension in Airway Smooth Muscle: A Strategy for Treating Airway Hyperresponsiveness in Asthma.Rho激酶对气道平滑肌主动力和被动张力的抑制作用：一种治疗哮喘气道高反应性的策略。
Biology (Basel). 2024 Feb 11;13(2):115. doi: 10.3390/biology13020115.
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Intrapulmonary airway smooth muscle is hyperreactive with a distinct proteome in asthma.在哮喘中，肺内气道平滑肌具有高反应性且拥有独特的蛋白质组。
Eur Respir J. 2020 Jul 2;56(1). doi: 10.1183/13993003.02178-2019. Print 2020 Jul.
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Upregulation of smooth muscle Rho-kinase protein expression in human asthma.人类哮喘中平滑肌 Rho 激酶蛋白表达上调。
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Airway smooth muscle hypertrophy and hyperplasia in asthma.哮喘中的气道平滑肌肥大和增生。
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Myocardin and ternary complex factors compete for SRF to control smooth muscle gene expression.心肌素与三元复合因子竞争血清反应因子，以控制平滑肌基因表达。
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Molecular mechanisms of phenotypic plasticity in smooth muscle cells.平滑肌细胞表型可塑性的分子机制
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Potent bronchoprotective effect of deep inspiration and its absence in asthma.深呼吸的强效支气管保护作用及其在哮喘中的缺失。
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Functional significance of increased airway smooth muscle in asthma and COPD.哮喘和慢性阻塞性肺疾病中气道平滑肌增加的功能意义。
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Regulation of bronchomotor tone by lung inflation in asthmatic and nonasthmatic subjects.哮喘患者和非哮喘患者中肺膨胀对支气管运动张力的调节
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