Sonoran Spine in collaboration with HonorHealth, 1255 W. Rio Salado Parkway, Suite 107, Tempe, AZ 85281, USA; Florida Advanced Spine and Orthopedics, 2040 Short Ave, Odessa, FL 33556, USA.
Sonoran Spine in collaboration with HonorHealth, 1255 W. Rio Salado Parkway, Suite 107, Tempe, AZ 85281, USA; Department of Anesthesia, University of Iowa Hospitals and Clinics, 200 Hawkins Dr, Iowa City, IA 52242, USA.
Spine J. 2024 Sep;24(9):1723-1731. doi: 10.1016/j.spinee.2024.04.022. Epub 2024 Apr 30.
Three-column spinal osteotomies (3-CO) are powerful techniques used to correct spinal deformity. These surgeries are associated with an elevated risk of complications. While outcomes have been reported in the literature with 2 years follow-up, longer-term outcomes of three-column osteotomies remain understudied.
This study aims to examine patient reported outcomes and complications for three-column osteotomies at 5 years.
Retrospective review of a prospectively collected spinal deformity cases database.
All consecutive adult patients at a single spine surgery center treated with either a pedicle subtraction osteotomy (PSO) or vertebral column resection (VCR) for spinal deformity, and with a minimum 5-year follow-up were included.
Visual-analog scale (VAS) for back pain score (0 to 10), Oswestry Disability Index (ODI) score (0 to 100), number of complications, revision rate, sagittal balance, lumbar lordosis at preoperative and at 5-year visit.
Data was extracted from a prospectively collected spinal deformity surgery database continuously updated since 2002 with data from operative reports, patients' medical visit notes and patients' self-reported VAS and ODI questionnaires completed at each office visit. Radiographic measurements were performed on standing full-length spine radiographs taken at preop and 5-year visits. Descriptive statistics, comparison of means and proportions among groups, and a logistic regression analysis were conducted using the statistical software package SPSS version 28. Statistical significance was set at p<.05.
Of 127 consecutive adult patients with minimum of 5-year follow-up undergoing a 3-CO posterior spinal surgery for spinal deformity were identified and included in the study, 79 (62%) were treated with PSO, and 48 (38%) with VCR. Both PSO and VCR groups demonstrated significant improvements in VAS (PSO preop: 6.7, 5-year: 4.6, p<.001; VCR preop: 7.1, 5-year: 5.2, p<.001), and ODI (PSO preop: 52.9, 5-year: 45.4, p<.001; VCR preop: 57.5, 5-year 43.0, p<.001) that were maintained at 5 years. Major and minor complications occurring within 5 years were not statistically different between the PSO and VCR groups (major: 59.5% vs 56.3%, p=.85; minor: 45.6% vs 37.5%, p=.46). The rate of revision surgery within 5 years was 39.4% overall. Of the fifty patients requiring revision, 37.5% were for nonunion, 27.1% instrumentation failure, 14.6% proximal junctional kyphosis (PJK), 12.5% vertebral fracture, 6.3% motor weakness, and 2.1% infection. Improvements in lumbar lordosis were maintained at 5 years in both the PSO (29.9° vs 47.2°, p<.001) and VCR (34.6° vs 48.5°, p<.001) groups while sagittal balance maintained significant improvement in the VCR group (9.5 cm vs 6.3 cm, p=.008) but not the PSO (11.4 cm vs 9.3 cm, p=.065).
Patients undergoing three-column osteotomies had a major complication rate of 57.5% and a minor complication rate of 42.5% after 5 years. Improvements in lumbar lordosis were maintained at 5-year follow-up, but sagittal balance was only maintained in the VCR group. Despite these radiographic findings, both VCR and PSO groups maintained significant clinical improvements in both VAS and ODI scores at 5-year follow up.
三柱截骨术(3-CO)是一种强大的技术,用于矫正脊柱畸形。这些手术与并发症的风险升高有关。虽然文献中已经报道了 2 年随访的结果,但三柱截骨术的长期结果仍研究不足。
本研究旨在检查三柱截骨术后 5 年患者的报告结果和并发症。
回顾性分析前瞻性收集的脊柱畸形病例数据库。
所有连续的成年患者,在单一脊柱手术中心接受经皮椎体后凸成形术(PSO)或脊柱全长切除术(VCR)治疗脊柱畸形,随访时间至少 5 年。
视觉模拟评分(VAS)背部疼痛评分(0 至 10)、Oswestry 残疾指数(ODI)评分(0 至 100)、并发症数量、翻修率、矢状位平衡、术前和 5 年随访时的腰椎前凸。
从 2002 年以来连续更新的前瞻性收集的脊柱畸形手术数据库中提取数据,数据来自手术报告、患者就诊记录以及患者每次就诊时自我报告的 VAS 和 ODI 问卷。在术前和 5 年随访时拍摄站立全长脊柱 X 线片进行放射学测量。使用 SPSS 版本 28 统计软件包进行描述性统计、组间均值和比例比较以及逻辑回归分析。统计学意义设定为 p<.05。
在接受三柱截骨术的 127 例连续成年患者中,有 79 例(62%)接受了 PSO,48 例(38%)接受了 VCR。PSO 和 VCR 组在 VAS(PSO 术前:6.7,5 年:4.6,p<.001;VCR 术前:7.1,5 年:5.2,p<.001)和 ODI(PSO 术前:52.9,5 年:45.4,p<.001;VCR 术前:57.5,5 年:43.0,p<.001)方面均有显著改善,且在 5 年内保持不变。PSO 和 VCR 组在 5 年内的主要和次要并发症发生率无统计学差异(主要:59.5% vs 56.3%,p=.85;次要:45.6% vs 37.5%,p=.46)。5 年内翻修手术率为 39.4%。在需要翻修的 50 名患者中,37.5%为不愈合,27.1%为器械失败,14.6%为近端交界性后凸(PJK),12.5%为椎体骨折,6.3%为运动无力,2.1%为感染。PSO(29.9° vs 47.2°,p<.001)和 VCR(34.6° vs 48.5°,p<.001)组的腰椎前凸在 5 年内均得到维持,而 VCR 组的矢状位平衡显著改善(9.5 cm 比 6.3 cm,p=.008),而 PSO 组无明显改善(11.4 cm 比 9.3 cm,p=.065)。
接受三柱截骨术的患者 5 年后主要并发症发生率为 57.5%,次要并发症发生率为 42.5%。5 年随访时,腰椎前凸得到维持,但仅在 VCR 组中维持矢状位平衡。尽管存在这些放射学发现,但 VCR 和 PSO 组在 5 年随访时 VAS 和 ODI 评分均保持显著改善。