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Improved survival with younger HLA-matched unrelated donors versus older matched sibling donor HCT with PTCy-prophylaxis.

作者信息

Ramdial Jeremy, Kebriaei Partow, Champlin Richard E, Popat Uday, Rezvani Katayoun, Shpall Elizabeth J, Mehta Rohtesh S

机构信息

MD Anderson Cancer Center, Houston, TX, USA.

Clinical Research Division, Fred Hutchinson Cancer Center, Seattle, WA, USA.

出版信息

Leukemia. 2024 Jun;38(6):1432-1434. doi: 10.1038/s41375-024-02256-0. Epub 2024 May 2.

DOI:10.1038/s41375-024-02256-0
PMID:38698071
Abstract
摘要

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本文引用的文献

1
Post-transplantation cyclophosphamide is associated with increased bacterial infections.移植后环磷酰胺与细菌感染增加有关。
Bone Marrow Transplant. 2024 Jan;59(1):76-84. doi: 10.1038/s41409-023-02131-z. Epub 2023 Oct 31.
2
Younger Matched Unrelated Donors Confer Decreased Relapse Risk Compared to Older Sibling Donors in Older Patients with B Cell Acute Lymphoblastic Leukemia Undergoing Allogeneic Hematopoietic Cell Transplantation.在接受异基因造血细胞移植的老年 B 细胞急性淋巴细胞白血病患者中，与年长的同胞供体相比，年轻的匹配无关供体可降低复发风险。
Transplant Cell Ther. 2023 Oct;29(10):611-618. doi: 10.1016/j.jtct.2023.07.015. Epub 2023 Jul 21.
3
Post-Transplantation Cyclophosphamide-Based Graft-versus-Host Disease Prophylaxis.
移植后环磷酰胺为基础的移植物抗宿主病预防。
N Engl J Med. 2023 Jun 22;388(25):2338-2348. doi: 10.1056/NEJMoa2215943.
4
Relapse and Disease-Free Survival in Patients With Myelodysplastic Syndrome Undergoing Allogeneic Hematopoietic Cell Transplantation Using Older Matched Sibling Donors vs Younger Matched Unrelated Donors.老年亲缘供者与年轻无关供者异基因造血细胞移植治疗骨髓增生异常综合征患者的复发和无病生存。
JAMA Oncol. 2022 Mar 1;8(3):404-411. doi: 10.1001/jamaoncol.2021.6846.
5
HLA-haploidentical vs matched unrelated donor transplants with posttransplant cyclophosphamide-based prophylaxis.HLA 单倍体相合与亲缘无关供者移植后应用环磷酰胺预防。
Blood. 2021 Jul 22;138(3):273-282. doi: 10.1182/blood.2021011281.
6
Development of an Unrelated Donor Selection Score Predictive of Survival after HCT: Donor Age Matters Most.无关供者选择评分的开发可预测 HCT 后的生存：供者年龄最重要。
Biol Blood Marrow Transplant. 2018 May;24(5):1049-1056. doi: 10.1016/j.bbmt.2018.02.006. Epub 2018 Feb 14.
7
Who is the better donor for older hematopoietic transplant recipients: an older-aged sibling or a young, matched unrelated volunteer?对于老年造血干细胞移植受者来说，谁是更好的供者：年龄较大的同胞供者还是年轻、匹配的无关志愿者？
Blood. 2013 Mar 28;121(13):2567-73. doi: 10.1182/blood-2012-08-453860. Epub 2013 Jan 29.