Wen Rui, Wang Miaoran, Bian Wei, Zhu Haoyue, Xiao Ying, Zeng Jing, He Qian, Wang Yu, Liu Xiaoqing, Shi Yangdi, Hong Zhe, Xu Bing
Shenyang Tenth People's Hospital, Shenyang, China.
Affiliated Central Hospital of Shenyang Medical College, Shenyang Medical College, Shenyang, China.
Front Neurol. 2024 Apr 18;15:1364952. doi: 10.3389/fneur.2024.1364952. eCollection 2024.
Timely intravenous thrombolysis (IVT) is crucial for improving outcomes in acute ischemic stroke (AIS) patients. This study evaluates the effectiveness of the Acute Stroke Care Map (ASCaM) initiative in Shenyang, aimed at reducing door-to-needle times (DNT) and thus improving the timeliness of care for AIS patients.
An retrospective cohort study was conducted from April 2019 to December 2021 in 30 hospitals participating in the ASCaM initiative in Shenyang. The ASCaM bundle included strategies such as EMS prenotification, rapid stroke triage, on-call stroke neurologists, immediate neuroimaging interpretation, and the innovative Pre-hospital Emergency Call and Location Identification feature. An interrupted time series analysis (ITSA) was used to assess the impact of ASCaM on DNT, comparing 9 months pre-intervention with 24 months post-intervention.
Data from 9,680 IVT-treated ischemic stroke patients were analyzed, including 2,401 in the pre-intervention phase and 7,279 post-intervention. The ITSA revealed a significant reduction in monthly DNT by -1.12 min and a level change of -5.727 min post-ASCaM implementation.
The ASCaM initiative significantly reduced in-hospital delays for AIS patients, demonstrating its effectiveness as a comprehensive stroke care improvement strategy in urban settings. These findings highlight the potential of coordinated care interventions to enhance timely access to reperfusion therapies and overall stroke prognosis.
及时进行静脉溶栓治疗对于改善急性缺血性脑卒中(AIS)患者的预后至关重要。本研究评估了沈阳市急性卒中护理地图(ASCaM)倡议的有效性,旨在缩短门到针时间(DNT),从而提高AIS患者的护理及时性。
2019年4月至2021年12月,在沈阳市参与ASCaM倡议的30家医院进行了一项回顾性队列研究。ASCaM综合措施包括急救医疗服务(EMS)预通知、快速卒中分诊、随叫随到的卒中神经科医生、即时神经影像解读以及创新的院前紧急呼叫和位置识别功能。采用中断时间序列分析(ITSA)评估ASCaM对DNT的影响,将干预前9个月与干预后24个月进行比较。
分析了9680例接受静脉溶栓治疗的缺血性卒中患者的数据,其中干预前阶段有2401例,干预后有7279例。ITSA显示,实施ASCaM后,每月DNT显著减少-1.12分钟,水平变化为-5.727分钟。
ASCaM倡议显著减少了AIS患者的院内延误,证明了其作为城市环境中综合卒中护理改善策略的有效性。这些发现凸显了协调护理干预在增强及时获得再灌注治疗和改善总体卒中预后方面的潜力。