Neurological Surgery Division, Department of Surgery, Obafemi Awolowo University Teaching Hospital Complex, Ile Ife, Osun state, Nigeria.
Childs Nerv Syst. 2024 Aug;40(8):2497-2503. doi: 10.1007/s00381-024-06437-1. Epub 2024 May 3.
A congenital encephalocele is the herniation of intracranial contents through skull defects of various sizes. Depending on the site, content, and size, it is associated with significant morbidity and mortality in children. There is a paucity of recent and comprehensive local clinical data regarding this anomaly. Understanding the peculiarities, clinical-pathologic profiles, and management challenges will help prevent and effectively manage congenital encephalocele to improve outcomes.
This was a retrospective study of all cases of congenital encephalocele managed between July 2000 and December 2023 at a tertiary hospital in the southwest region of Nigeria. Relevant demographic, clinicopathological, and management data were retrieved and analysed.
There were 31 females and 11 males. Their ages ranged from 3 hours to 24 years. Sixteen (35.3%) were delivered in a non-health facility. Birth asphyxia was reported in 5 babies. Few mothers (4.8%) used preconception folic acid. Anaemia (n = 5) and sepsis (n = 4) were the common preoperative morbidities. All patients had definitive surgery, with 18 operated on within the first month of life. Cerebrospinal fluid (CSF) leak was the most common postoperative complication and was significantly observed in the sincipital group (p = 0.018). Thirty-one patients (73.8%) presented for follow-up after surgery, and the mean follow-up duration was 26.6 weeks. Mortality was recorded in a patient (2.4%) due to Klebsiella meningitis.
Congenital encephaloceles are relatively common in our setting. Therefore, there is a need to address the associated poor maternal and neonatal health conditions. Early surgery can be performed with a favourable outcome.
先天性脑膨出是由于颅骨大小不同的缺陷导致颅内内容物疝出。根据部位、内容物和大小的不同，它与儿童的高发病率和死亡率密切相关。目前，关于这种异常的最新且全面的本地临床数据较少。了解其特殊性、临床病理特征和管理挑战，有助于预防和有效管理先天性脑膨出，以改善预后。
这是一项回顾性研究，对 2000 年 7 月至 2023 年 12 月期间在尼日利亚西南部一家三级医院治疗的所有先天性脑膨出患者的病例进行了研究。检索并分析了相关的人口统计学、临床病理和管理数据。
患者中女性 31 例，男性 11 例，年龄 3 小时至 24 岁。16 例（35.3%）在非医疗机构分娩。5 例患儿有出生窒息史。少数母亲（4.8%）在受孕前使用过叶酸。贫血（n=5）和败血症（n=4）是常见的术前合并症。所有患者均行确定性手术，其中 18 例在出生后第一个月内接受手术。脑脊液（CSF）漏是最常见的术后并发症，在前囟组中发生率显著更高（p=0.018）。31 例患者（73.8%）在手术后接受了随访，平均随访时间为 26.6 周。1 例患者（2.4%）因肺炎克雷伯菌脑膜炎而死亡。
先天性脑膨出在我们的环境中较为常见。因此，需要解决与之相关的孕产妇和新生儿健康状况较差的问题。早期手术可以获得良好的结果。
