VIB Bioimaging Core Ghent, VIB, Zwijnaarde, Belgium.
VIB Center for Inflammation Research, Ghent University, Zwijnaarde, Belgium.
J Microsc. 2024 Jun;294(3):411-419. doi: 10.1111/jmi.13314. Epub 2024 May 3.
Centralised core facilities have evolved into vital components of life science research, transitioning from a primary focus on centralising equipment to ensuring access to technology experts across all facets of an experimental workflow. Herein, we put forward a seven-pillar model to define what a core facility needs to meet its overarching goal of facilitating research. The seven equally weighted pillars are Technology, Core Facility Team, Training, Career Tracks, Technical Support, Community and Transparency. These seven pillars stand on a solid foundation of cultural, operational and framework policies including the elements of transparent and stable funding strategies, modern human resources support, progressive facility leadership and management as well as clear institute strategies and policies. This foundation, among other things, ensures a tight alignment of the core facilities to the vision and mission of the institute. To future-proof core facilities, it is crucial to foster all seven of these pillars, particularly focusing on newly identified pillars such as career tracks, thus enabling core facilities to continue supporting research and catalysing scientific advancement. Lay abstract: In research, there is a growing trend to bring advanced, high-performance equipment together into a centralised location. This is done to streamline how the equipment purchase is financed, how the equipment is maintained, and to enable an easier approach for research scientists to access these tools in a location that is supported by a team of technology experts who can help scientists use the equipment. These centralised equipment centres are called Core Facilities. The core facility model is relatively new in science and it requires an adapted approach to how core facilities are built and managed. In this paper, we put forward a seven-pillar model of the important supporting elements of core facilities. These supporting elements are: Technology (the instruments themselves), Core Facility Team (the technology experts who operate the instruments), Training (of the staff and research community), Career Tracks (for the core facility staff), Technical Support (the process of providing help to apply the technology to a scientific question), Community (of research scientist, technology experts and developers) and Transparency (of how the core facility works and the costs associated with using the service). These pillars stand on the bigger foundation of clear policies, guidelines, and leadership approaches at the institutional level. With a focus on these elements, the authors feel core facilities will be well positioned to support scientific discovery in the future.
集中式核心设施已发展成为生命科学研究的重要组成部分,其重点已从集中设备转变为确保在实验工作流程的各个方面都能获得技术专家的支持。在此,我们提出了一个七支柱模型来定义核心设施需要满足的条件,以实现促进研究的总体目标。这七个同样重要的支柱是技术、核心设施团队、培训、职业发展轨道、技术支持、社区和透明度。这七个支柱建立在坚实的文化、运营和框架政策基础上,包括透明和稳定的资金策略、现代人力资源支持、渐进式设施领导和管理以及明确的机构战略和政策等要素。除其他事项外,这些基础确保了核心设施与机构的愿景和使命紧密一致。为了使核心设施具有前瞻性,必须培养这七个支柱,特别是要关注新出现的职业发展轨道等支柱,从而使核心设施能够继续支持研究并促进科学进步。
研究中,有一种越来越流行的趋势,即将先进的、高性能的设备集中到一个中心位置。这样做是为了简化设备采购的融资方式、设备的维护方式,以及为研究科学家提供一种更简单的方法,让他们可以在一个由技术专家团队支持的地点获得这些工具,这些技术专家可以帮助科学家使用这些设备。这些集中的设备中心称为核心设施。核心设施模型在科学领域相对较新,需要对核心设施的建设和管理方式进行适应性调整。在本文中,我们提出了一个核心设施的七个支柱模型,这七个支柱是核心设施的重要支撑要素。这些支撑要素是:技术(仪器本身)、核心设施团队(操作仪器的技术专家)、培训(员工和研究社区)、职业发展轨道(核心设施员工)、技术支持(向研究人员提供帮助以将技术应用于科学问题的过程)、社区(研究科学家、技术专家和开发人员)和透明度(核心设施的工作方式和使用服务相关的成本)。这些支柱建立在机构层面清晰的政策、准则和领导方法的更大基础上。作者认为,重点关注这些要素将使核心设施能够很好地定位,以支持未来的科学发现。