O'Rourke I C
Aust N Z J Surg. 1985 Aug;55(4):347-54. doi: 10.1111/j.1445-2197.1985.tb00898.x.
Ninety-two patients with severe gastro-oesophageal reflux submitted to fundoplication from 1979 to 1984 have been studied. Severity of symptoms pre- and postoperatively have been assessed using a symptom score. The mean pre-operative score was 5.39 out of 9. A standard procedure for the fundoplication was used, including a long (5 cm) wrap leaving the wrap in an intrathoracic position when it could not be brought completely into the abdomen. Vagotomy was added in 53 patients. Posterior gastropexy was used in 54 patients. There was a zero incidence of damage to the spleen and a zero mortality. The mean symptom score on follow up was 0.41 out of 9 with 90.5% patients having absent or minimal symptoms. However, only 68% remained satisfied with their overall results. The incidence of sequelae related to the procedure itself including gas bloat (19.6%), dumping (7.6%) diarrhoea (6.5%) and development of gastric ulcer (2.2%) explained this discrepancy. The addition of vagotomy did not improve the results but added its complications especially dumping and diarrhoea. There were no differences in clinical results whether the fundoplication had been left in the chest or in the abdomen but there were two hazardous complications of the intrathoracic fundoplication including a perforated gastric fundus and a gastric ulcer in the thoracic part of the stomach. Posterior gastropexy conferred no benefit to the results. Measures which might improve results include: avoidance of vagotomy, intrathoracic fundoplication and gastropexy; shortening the wrap; and the use of a 50-60 F dilator in the oesophagus during the wrap.
对1979年至1984年间接受胃底折叠术的92例严重胃食管反流患者进行了研究。术前和术后症状的严重程度采用症状评分进行评估。术前平均评分为9分制中的5.39分。采用标准的胃底折叠术式,包括5厘米长的包绕,当包绕无法完全放入腹腔时将其置于胸腔内。53例患者加行了迷走神经切断术。54例患者采用了胃后固定术。脾脏损伤发生率为零,死亡率为零。随访时平均症状评分为9分制中的0.41分,90.5%的患者症状消失或轻微。然而,只有68%的患者对总体结果仍感满意。与手术本身相关的后遗症发生率,包括气胀(19.6%)、倾倒综合征(7.6%)、腹泻(6.5%)和胃溃疡形成(2.2%),解释了这种差异。加行迷走神经切断术并未改善结果,反而增加了并发症,尤其是倾倒综合征和腹泻。胃底折叠术置于胸腔或腹腔,临床结果并无差异,但胸腔内胃底折叠术有两种严重并发症,包括胃底穿孔和胃胸段溃疡。胃后固定术对结果并无益处。可能改善结果的措施包括:避免行迷走神经切断术、胸腔内胃底折叠术和胃固定术;缩短包绕;以及在包绕过程中使用50 - 60F的食管扩张器。