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从新生儿中获得的见解,解决成人脊髓修复的挑战。

Addressing challenges for repairing adult spinal cord with insights from neonates.

机构信息

Department of Neurological Surgery, University of California, San Diego, La Jolla, CA 92037, USA.

Department of Neurological Surgery, Orlando Health, Orlando, FL, USA.

出版信息

Cell Stem Cell. 2024 May 2;31(5):585-586. doi: 10.1016/j.stem.2024.04.008.

Abstract

Stem cell therapy has emerged as a promising area of scientific investigation, sparking considerable interest, especially in spinal cord injury (SCI). Sun et al. discover that the extracellular matrix (ECM) from the neonatal spinal cord transmits biochemical signals to endogenous axons, thus promoting axonal regeneration.

摘要

干细胞治疗已成为科学研究中一个有前途的领域,引起了相当大的兴趣,特别是在脊髓损伤(SCI)方面。孙等人发现,新生儿脊髓的细胞外基质(ECM)向内源性轴突传递生化信号,从而促进轴突再生。

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