Department of Medicine, University Health Truman Medical Center, University of Missouri-Kansas City, Kansas City, MO.
Department of Medicine, Wright State University Boonshoft School of Medicine, Dayton, Ohio.
Am J Med Sci. 2024 Nov;368(5):532-537. doi: 10.1016/j.amjms.2024.04.020. Epub 2024 May 1.
The QT interval, an electrocardiographic temporal representation of the ventricular depolarization and repolarization, is an integral parameter that must be carefully evaluated to gather critical information regarding electrical instability that may cause malignant ventricular dysrhythmias or sudden cardiac death. The QT interval is affected by several inheritable and acquired factors, such as genetic mutations, electrolyte disturbances, and medication interactions. We strongly believe that prompt and accurate recognition of any QT interval abnormalities is critical in many clinical settings. This concise review article highlights the importance of accurate measurement of the QT interval, enhances understanding of the most prevalent factors yielding abnormalities within the QT interval and the prognostic value of the QT interval, as well as provides several key practical reminders for healthcare professionals to strengthen our clinical practice.
QT 间期是心室去极化和复极化的心电图时间表示,是一个必需的重要参数,必须仔细评估,以收集有关可能导致恶性室性心律失常或心源性猝死的电不稳定性的关键信息。QT 间期受多种遗传和获得性因素的影响,如基因突变、电解质紊乱和药物相互作用。我们坚信,在许多临床情况下,及时准确地识别任何 QT 间期异常都至关重要。这篇简明的综述文章强调了准确测量 QT 间期的重要性,增强了对导致 QT 间期异常的最常见因素以及 QT 间期的预后价值的理解,并为医疗保健专业人员提供了一些关键的实用提示,以加强我们的临床实践。