Department of Obstetrics and Gynecology, General Hospital Zadar, Bože Peričića 5, 23000, Zadar, Croatia.
Department of Obstetrics and Gynaecology, Imelda Hospital, Bonheiden, Belgium.
Arch Gynecol Obstet. 2024 Jun;309(6):2395-2400. doi: 10.1007/s00404-024-07531-0. Epub 2024 May 4.
The purpose of this systematic review is to present and compare results from studies that have been using autologous tissue for POP repair.
Systematic review was done according to the Cochrane Handbook for Systematic Reviews. We aimed to retrieve reports of published and ongoing studies on the efficacy and safety of autologous tissue in vaginal vault prolapse repair. The databases searched were MEDLINE (PubMed interface), Scopus, Cohrane Central Register of Controlled Trials (CENTRAL) and ClinicalTrials.gov.
The success rate varied among studies. In fascia-lata group success rate reports varied from 83 to a 100%, with a median follow-up from 12 to 52 months among studies. Rectus fascia reported success rates from 87 to a 100% with a follow-up of 12 months to longest of 98 months.
Autologous tissues show satisfying outcomes in terms of safety and efficacy. Sacrocolpopexy procedure with fascia lata has better outcome in term of treatment of prolapse. Harvesting place on lateral side of buttock has more complications in comparison with rectus fascia but size of the graft can be wider in fascia-lata group.
本系统评价旨在介绍和比较使用自体组织修复 POP 的研究结果。
根据 Cochrane 系统评价手册进行系统评价。我们旨在检索关于阴道穹窿脱垂修复中自体组织疗效和安全性的已发表和正在进行的研究报告。检索的数据库包括 MEDLINE(PubMed 接口)、Scopus、Cochrane 对照试验中心注册库(CENTRAL)和 ClinicalTrials.gov。
不同研究的成功率不同。在阔筋膜组中,成功率报告从 83%到 100%不等,研究的中位随访时间从 12 个月到 52 个月不等。腹直肌筋膜报告的成功率从 87%到 100%,随访时间从 12 个月到最长的 98 个月不等。
自体组织在安全性和疗效方面表现出令人满意的结果。阔筋膜骶骨阴道固定术在治疗脱垂方面有更好的效果。与腹直肌筋膜相比,臀部外侧取筋膜的并发症更多,但阔筋膜组的移植物尺寸可以更宽。