Lima Francisco Veríssimo Perrout, Andrade Diana de Medeiros, Filho José Elias, Souza Pedro Lima, Azevedo Luciene Ferreira, Coelho Marcelo Martins, de Lima Jorge Roberto Perrout, Trevizan Patrícia Fernandes, Laterza Mateus Camaroti, Martinez Daniel Godoy
Cardiovascular Research Unit and Exercise Physiology, Federal University of Juiz de Fora, Brazil. José Lourenço Kelmer, s/n, Martelos, Juiz de Fora 36036-900, Brazil.
Cardiovascular Research Unit and Exercise Physiology, Federal University of Juiz de Fora, Brazil. José Lourenço Kelmer, s/n, Martelos, Juiz de Fora 36036-900, Brazil.
Int J Cardiol. 2024 Aug 1;408:132106. doi: 10.1016/j.ijcard.2024.132106. Epub 2024 May 3.
Ultramarathon running poses physiological challenges, impacting cardiac function. This systematic review and meta-analysis explore the acute effects of single-stage ultramarathon running on cardiac function.
Preferred Reporting Items for Systematic Reviews and Meta-Analyses recommendations were followed. Searches covered Medline, Embase, CINAHL, SPORTDiscus, Web of Science, Central Cochrane, and Scopus. Random effects meta-analyses assessed left ventricular (LV) and right ventricular (RV) variables, expressed as mean differences (MD) with 95% confidence intervals (CI).
Among 6972 studies, 17 were included. Post-ultramarathon reductions were found in LV end-diastolic diameter (LVEDD) (-1.24; 95% CI = -1.77, -0.71 mm), LV end-diastolic volume (LVEDV) (-9.92; 95% CI = -15.25, -4.60 ml), LV stroke volume (LVSV) (-8.96 ml, 95% CI -13.20, -4.72 ml), LV ejection fraction (LVEF) (-3.71; 95% CI = -5.21, -2.22%), LV global longitudinal strain (LVGLS) (-1.48; 95% CI = -2.21, -0.76%), E/A (-0.30; 95% CI = -0.38, -0.22 cm/s), .E' (-1.35 cm/s, 95% CI -1.91, -0.79 cm/s), RV fractional area change (RVFAC) (-3.34, 95% CI = -5.84, -0.84%), tricuspid annular plane systolic excursion (TAPSE) (-0.12, 95% CI = -0.22, -0.02 cm), RV global longitudinal strain (RVGLS) (-1.73, 95% CI = -2.87, -0.59%), with increases in RV end-diastolic area (RVEDA) (1.89, 95% CI = 0.63, 3.14 cm), RV Peak A' (1.32 cm/s, 95% CI 0.20, 2.44), and heart rate (18.24, 95% CI = 15.16, 21.32). No significant differences were observed in LV end-systolic diameter (LVESD), LV end-systolic volume (LVESV), RV end-diastolic diameter (RVEDD), RV Peak E', and RV Peak S'.
Evidence suggests immediate impairment of systolic and diastolic cardiac function post-ultramarathon running.
超级马拉松跑步会带来生理挑战，影响心脏功能。本系统评价和荟萃分析探讨单阶段超级马拉松跑步对心脏功能的急性影响。
遵循系统评价和荟萃分析的首选报告项目建议。检索范围包括Medline、Embase、CINAHL、SPORTDiscus、科学网、Cochrane中心对照试验注册库和Scopus。随机效应荟萃分析评估左心室（LV）和右心室（RV）变量，以平均差（MD）和95%置信区间（CI）表示。
在6972项研究中，纳入了17项。超级马拉松赛后，左心室舒张末期直径（LVEDD）（-1.24；95%CI=-1.77，-0.71mm）、左心室舒张末期容积（LVEDV）（-9.92；95%CI=-15.25，-4.60ml）、左心室每搏输出量（LVSV）（-8.96ml，95%CI -13.20，-4.72ml）、左心室射血分数（LVEF）（-3.71；95%CI=-5.21，-2.22%）、左心室整体纵向应变（LVGLS）（-1.48；95%CI=-2.21，-0.76%）、E/A（-0.30；95%CI=-0.38，-0.22cm/s）、E'（-1.35cm/s，95%CI -1.91，-0.79cm/s）、右心室面积变化分数（RVFAC）（-3.34，95%CI=-5.84，-0.84%）、三尖瓣环平面收缩期位移（TAPSE）（-0.12，95%CI=-0.22，-0.02cm）、右心室整体纵向应变（RVGLS）（-1.73，95%CI=-2.87，-0.59%）降低，右心室舒张末期面积（RVEDA）（1.89，95%CI=0.63，3.14cm）、右心室A'峰值（1.32cm/s，95%CI 0.20，2.44）和心率（18.24，95%CI=
