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性别对自发性脑出血(sICH)的流行病学、管理和结局的影响。

The impact of sex on epidemiology, management, and outcome of spontaneous intracerebral hemorrhage (sICH).

机构信息

Rush University Medical Center, Division of Critical Care Neurology, Department of Neurological Sciences.

Rush University Medical Center, Division of Critical Care Neurology, Department of Neurological Sciences.

出版信息

J Stroke Cerebrovasc Dis. 2024 Jul;33(7):107755. doi: 10.1016/j.jstrokecerebrovasdis.2024.107755. Epub 2024 May 4.

DOI:10.1016/j.jstrokecerebrovasdis.2024.107755
PMID:38705497
Abstract

OBJECTIVE

Data on sex differences in spontaneous intracerebral hemorrhages are limited.

METHODS

An automated comprehensive scoping literature review was performed using PubMed and Scopus. Articles written in English about spontaneous intracerebral hemorrhage and sex were reviewed.

RESULTS

Males experience spontaneous intracerebral hemorrhage more frequently than females, at younger ages, and have a higher prevalence of deep bleeds compared to females. Risk factors between sexes vary and may contribute to differing incidences and locations of spontaneous intracranial hemorrhage. Globally, females receive less aggressive care than males, likely impacting survival.

CONCLUSIONS

Epidemiology, risk factors, and treatment of spontaneous intracranial hemorrhage vary by sex, with limited and oftentimes conflicting data available. Further research into the sex-based differences of spontaneous intracranial hemorrhage is necessary for clinicians to better understand how to evaluate and guide treatment in the future.

摘要

目的

自发性脑出血中性别差异的数据有限。

方法

使用 PubMed 和 Scopus 进行了自动化全面文献综述。对有关自发性脑出血和性别的英文文章进行了回顾。

结果

男性比女性更频繁地发生自发性脑出血,年龄更小,与女性相比,深部出血的患病率更高。男女之间的危险因素不同,可能导致自发性颅内出血的发生率和位置不同。全球范围内,女性接受的治疗不如男性积极,这可能会影响生存率。

结论

自发性脑出血的流行病学、危险因素和治疗因性别而异,可用的数据有限且常常相互矛盾。进一步研究自发性脑出血的性别差异对于临床医生更好地了解如何在未来进行评估和指导治疗非常必要。

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J Stroke Cerebrovasc Dis. 2024 Jul;33(7):107755. doi: 10.1016/j.jstrokecerebrovasdis.2024.107755. Epub 2024 May 4.
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引用本文的文献

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The causal relationship between enlarged perivascular spaces and intracerebral hemorrhage: A 2-sample Mendelian randomization study.血管周围间隙扩大与脑出血之间的因果关系:一项双样本孟德尔随机化研究。
Medicine (Baltimore). 2025 Jun 6;104(23):e42658. doi: 10.1097/MD.0000000000042658.
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Intracerebral Hemorrhage.脑出血
Cerebrovasc Dis Extra. 2025;15(1):1-8. doi: 10.1159/000542566. Epub 2024 Nov 18.