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预测烧伤后 6 个月至 2 年内 DSM-5 PTSD 症状:早期心理风险因素的作用。

Predicting DSM-5 PTSD symptomatology 6 months to 2 years after burn: The role of early psychological risk factors.

机构信息

Graduate Institute of Behavioral Sciences, Chang Gung University, Taoyuan, Taiwan; Department of Psychiatry, Chang Gung Memorial Hospital, Linkou, Taoyuan, Taiwan.

出版信息

Burns. 2024 Sep;50(7):1898-1907. doi: 10.1016/j.burns.2024.04.011. Epub 2024 Apr 26.

Abstract

BACKGROUND

Major burn injuries may have long-term mental health consequences, such as posttraumatic stress disorder (PTSD). This study extended prior work to investigate DSM-5 PTSD symptoms at 6 months, 1 year, and 2 years post-burn as well as the contribution of two sets of early psychological risk factors to DSM-5 PTSD symptoms: Established PTSD risk factors (prior adjustment problems, past trauma, perception of life threat, peritraumatic emotions and dissociation) and theory-derived cognitive factors (negative appraisals of the trauma and its sequelae, memory disorganization, trauma-related rumination, and thought suppression).

METHOD

The current study recruited a sample of 118 adult burn patients (75.4% men, mean age 41.8, mean TBSA 18.3%) consecutively admitted to a large regional burn center in Northern Taiwan, who were assessed at 6, 12, and 24 months following their burn injury.

RESULTS

A total of 11.0%, 5.9%, and 7.6% met probable DSM-5 PTSD at 6 months, 1 year, and 2 years post-burn, respectively. The rates rose to 15.3%, 10.2%, and 11.0% using the cutoff method. After controlling for covariates, the regression model with theory-derived cognitive factors explained an additional significant 15.9%, 17.2%, and 17.7% of the variance in DSM-5 PTSD symptoms at 6 months, 1 year, and 2 years post-burn, respectively. In contrast, the regression model with established PTSD risk factors explained an additional significant 7.2%, 14.4%, and 10.5% of the variance in DSM-5 PTSD symptoms at 6 months, 1 year, and 2 years post-burn, respectively. Of all predictors, negative appraisals of intrusions was consistently and strongly predictive of DSM-5 PTSD symptomatology post-burn across time, followed by prior depression.

CONCLUSIONS

The results underscore the role of early cognitive risk factors in the development and persistence of DSM-5 PTSD symptomatology following burn injury.

摘要

背景

严重烧伤可能会导致长期的心理健康后果,例如创伤后应激障碍(PTSD)。本研究扩展了先前的工作,以调查烧伤后 6 个月、1 年和 2 年的 DSM-5 PTSD 症状,以及两组早期心理风险因素对 DSM-5 PTSD 症状的贡献:已确立的 PTSD 风险因素(先前的适应问题、过去的创伤、生命威胁感知、创伤时情绪和分离)和理论衍生的认知因素(对创伤及其后果的负面评价、记忆组织不良、与创伤相关的反刍、思维抑制)。

方法

本研究招募了 118 名成年烧伤患者(75.4%为男性,平均年龄 41.8 岁,平均 TBSA 为 18.3%),他们连续入住台湾北部一家大型地区烧伤中心,在烧伤后 6、12 和 24 个月进行评估。

结果

分别有 11.0%、5.9%和 7.6%的患者在烧伤后 6 个月、1 年和 2 年内符合 DSM-5 PTSD 的可能诊断。使用截止值方法,这些比率分别上升至 15.3%、10.2%和 11.0%。在控制协变量后,具有理论衍生认知因素的回归模型分别解释了 DSM-5 PTSD 症状在烧伤后 6 个月、1 年和 2 年时额外的 15.9%、17.2%和 17.7%的可变性。相比之下,具有已确立的 PTSD 风险因素的回归模型分别解释了 DSM-5 PTSD 症状在烧伤后 6 个月、1 年和 2 年时额外的 7.2%、14.4%和 10.5%的可变性。在所有预测因素中,对侵入性的负面评价始终如一地强烈预测了烧伤后各个时间点的 DSM-5 PTSD 症状,其次是先前的抑郁。

结论

这些结果强调了早期认知风险因素在烧伤后发展和持续存在 DSM-5 PTSD 症状中的作用。

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