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多发性骨髓瘤患者因播散性带状疱疹死亡:一例报告及文献复习

Death Caused by Disseminated Herpes Zoster in a Patient with Multiple Myeloma: A Case Report and Literature Review.

作者信息

Bo Yang, Zhong Xiaojing, Xiang Yanping, Ren Qingjun, Hao Pingsheng

机构信息

Department of Dermatology, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, People's Republic of China.

出版信息

Clin Cosmet Investig Dermatol. 2024 Apr 27;17:941-951. doi: 10.2147/CCID.S464039. eCollection 2024.

Abstract

We report a fatal case of disseminated herpes zoster in a patient with multiple myeloma, illustrating the severe risks immunocompromised individuals face from viral infections. By combining a detailed case report with an extensive literature review, the paper seeks to shed light on the underlying susceptibility factors for varicella-zoster virus infection in multiple myeloma patients. We further evaluate effective prophylactic protocols for herpes zoster, aiming to equip clinicians with improved therapeutic strategies. The case underscores the critical need for vigilant clinical assessments and tailored patient management to mitigate infection risks and enhance patient outcomes.

摘要

我们报告了一例多发性骨髓瘤患者发生播散性带状疱疹的致死病例,该病例说明了免疫功能低下个体面临的病毒感染严重风险。通过将详细的病例报告与广泛的文献综述相结合,本文旨在阐明多发性骨髓瘤患者感染水痘-带状疱疹病毒的潜在易感因素。我们进一步评估了带状疱疹的有效预防方案,旨在为临床医生提供更好的治疗策略。该病例强调了进行警惕的临床评估和针对性患者管理以降低感染风险并改善患者预后的迫切需求。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/941b/11066659/883d846eb6ae/CCID-17-941-g0001.jpg

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