Garcia Joshua M, Wu Patrick B, Haddadin Ramez I, Kang J Minjy
Department of Ophthalmology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Am J Ophthalmol Case Rep. 2024 Apr 18;34:102048. doi: 10.1016/j.ajoc.2024.102048. eCollection 2024 Jun.
To describe the presentation of lacrimal gland secretions mimicking a positive Seidel test following combined complex cataract surgery and endocyclophotocoagulation (ECP).
The patient presented with a posterior subcapsular cataract (PSC) most likely secondary to chronic steroid use for a history of chemical burns from a firework injury in 2019. This injury resulted in symblepharon formation and limbal stem cell deficiency. He also developed glaucoma secondary to steroid response and angle structure damage. On postoperative day 1 (POD 1) after combined cataract surgery and ECP, the patient's paracentesis was Seidel positive and aqueous suppression was started. On postoperative week 1 (POW 1), the paracentesis was Seidel negative; however, it was noted at this visit that there were 3 pinpoint areas in the superotemporal conjunctiva that were Seidel positive. Digital pressure did not worsen the leak. Ultrasound biomicroscopy (UBM) was performed at POW 2.5 and showed lacrimal gland ducts in the superotemporal conjunctiva. Given this, it is likely that the "Seidel positive" finding was not due to aqueous humor leakage, but secretions from lacrimal gland tissue that may have been dragged more anteriorly due to conjunctiva scarring, thus producing a false positive Seidel sign.
CONCLUSION & IMPORTANCE: This case highlights a false positive Seidel sign in the context of an eye with a complex ocular history and recent surgery. Clinicians should recognize that a false positive Seidel sign is possible if normal lacrimal gland anatomy has been disturbed.
描述在复杂性白内障手术联合眼内睫状体光凝术(ECP)后出现类似Seidel试验阳性的泪腺分泌物表现。
患者患有后囊下白内障(PSC),很可能继发于2019年烟花爆炸致化学烧伤病史后长期使用类固醇。此次损伤导致睑球粘连形成和角膜缘干细胞缺乏。他还因类固醇反应和房角结构损害继发青光眼。在白内障手术联合ECP术后第1天(POD 1),患者前房穿刺Seidel试验阳性,开始进行前房抑制。术后第1周(POW 1),前房穿刺Seidel试验阴性;然而,此次检查发现颞上结膜有3个针尖样区域Seidel试验阳性。指压并未使渗漏加重。在术后2.5周进行了超声生物显微镜检查(UBM),显示颞上结膜有泪腺导管。据此,“Seidel试验阳性”发现很可能并非由于房水渗漏,而是泪腺组织的分泌物,可能因结膜瘢痕形成而被牵拉至更靠前位置,从而产生了假阳性Seidel征。
该病例凸显了在具有复杂眼部病史且近期接受手术的眼中出现的假阳性Seidel征。临床医生应认识到,如果正常泪腺解剖结构受到干扰,可能会出现假阳性Seidel征。