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复杂白内障手术后副泪腺分泌模拟Seidel征阳性:病例报告

Accessory lacrimal gland secretion mimicking seidel positivity following complex cataract surgery: Case report.

作者信息

Garcia Joshua M, Wu Patrick B, Haddadin Ramez I, Kang J Minjy

机构信息

Department of Ophthalmology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.

出版信息

Am J Ophthalmol Case Rep. 2024 Apr 18;34:102048. doi: 10.1016/j.ajoc.2024.102048. eCollection 2024 Jun.

DOI:10.1016/j.ajoc.2024.102048
PMID:38707948
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11066134/
Abstract

PURPOSE

To describe the presentation of lacrimal gland secretions mimicking a positive Seidel test following combined complex cataract surgery and endocyclophotocoagulation (ECP).

OBSERVATION

The patient presented with a posterior subcapsular cataract (PSC) most likely secondary to chronic steroid use for a history of chemical burns from a firework injury in 2019. This injury resulted in symblepharon formation and limbal stem cell deficiency. He also developed glaucoma secondary to steroid response and angle structure damage. On postoperative day 1 (POD 1) after combined cataract surgery and ECP, the patient's paracentesis was Seidel positive and aqueous suppression was started. On postoperative week 1 (POW 1), the paracentesis was Seidel negative; however, it was noted at this visit that there were 3 pinpoint areas in the superotemporal conjunctiva that were Seidel positive. Digital pressure did not worsen the leak. Ultrasound biomicroscopy (UBM) was performed at POW 2.5 and showed lacrimal gland ducts in the superotemporal conjunctiva. Given this, it is likely that the "Seidel positive" finding was not due to aqueous humor leakage, but secretions from lacrimal gland tissue that may have been dragged more anteriorly due to conjunctiva scarring, thus producing a false positive Seidel sign.

CONCLUSION & IMPORTANCE: This case highlights a false positive Seidel sign in the context of an eye with a complex ocular history and recent surgery. Clinicians should recognize that a false positive Seidel sign is possible if normal lacrimal gland anatomy has been disturbed.

摘要

目的

描述在复杂性白内障手术联合眼内睫状体光凝术(ECP)后出现类似Seidel试验阳性的泪腺分泌物表现。

观察

患者患有后囊下白内障(PSC),很可能继发于2019年烟花爆炸致化学烧伤病史后长期使用类固醇。此次损伤导致睑球粘连形成和角膜缘干细胞缺乏。他还因类固醇反应和房角结构损害继发青光眼。在白内障手术联合ECP术后第1天(POD 1),患者前房穿刺Seidel试验阳性,开始进行前房抑制。术后第1周(POW 1),前房穿刺Seidel试验阴性;然而,此次检查发现颞上结膜有3个针尖样区域Seidel试验阳性。指压并未使渗漏加重。在术后2.5周进行了超声生物显微镜检查(UBM),显示颞上结膜有泪腺导管。据此,“Seidel试验阳性”发现很可能并非由于房水渗漏,而是泪腺组织的分泌物,可能因结膜瘢痕形成而被牵拉至更靠前位置,从而产生了假阳性Seidel征。

结论与意义

该病例凸显了在具有复杂眼部病史且近期接受手术的眼中出现的假阳性Seidel征。临床医生应认识到,如果正常泪腺解剖结构受到干扰,可能会出现假阳性Seidel征。

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本文引用的文献

1
Effects of aqueous suppressants and prostaglandin analogues on early wound healing after glaucoma implant surgery.水抑制剂和前列腺素类似物对青光眼植入术后早期伤口愈合的影响。
Sci Rep. 2019 Mar 27;9(1):5251. doi: 10.1038/s41598-019-41790-1.
2
Open Globe: Corneal Laceration Injury with Negative Seidel Sign.开放性眼球:角膜裂伤且Seidel征阴性。
Clin Pract Cases Emerg Med. 2018 Jun 12;2(3):266-267. doi: 10.5811/cpcem.2018.4.38086. eCollection 2018 Aug.
3
Beta-adrenergic receptor agonists delay while antagonists accelerate epithelial wound healing: evidence of an endogenous adrenergic network within the corneal epithelium.
β-肾上腺素能受体激动剂会延迟而拮抗剂会加速上皮伤口愈合:角膜上皮内存在内源性肾上腺素能网络的证据。
J Cell Physiol. 2007 Apr;211(1):261-72. doi: 10.1002/jcp.20934.
4
Downward extension of the lacrimal gland under the bulbar conjunctiva after trabeculectomy.小梁切除术后泪腺在球结膜下向下延伸。
J Glaucoma. 2001 Aug;10(4):358-60. doi: 10.1097/00061198-200108000-00018.
5
A false-positive Seidel test after Ahmed valve insertion.
Ophthalmic Surg Lasers. 1999 Apr;30(4):313-4.
6
A new technique for the treatment of lacrimal gland prolapse in blepharoplasty.一种在眼睑成形术中治疗泪腺脱垂的新技术。
Aesthetic Plast Surg. 1994 Winter;18(1):65-9. doi: 10.1007/BF00444250.