College of Environmental Science & Engineering, Guangzhou University, Guangzhou, 510006, China.
School of Chemistry, South China Normal University, Guangzhou, 510006, China.
Mikrochim Acta. 2024 May 6;191(6):302. doi: 10.1007/s00604-024-06390-5.
A sensitive and biocompatible N-rich probe for rapid visual uranium detection was constructed by grafting two trianiline groups to 2,6-bis(aminomethyl)pyridine. Possessing excellent aggregation-induced emission (AIE) property and the advantages to form multidentate chelate with U selectively, the probe has been applied successfully to visualize uranium in complex environmental water samples and living cells, demonstrating outstanding anti-interference ability against large equivalent of different ions over a wide effective pH range. A large linear range (1.0 × 10-9.0 × 10 mol/L) and low detection limit (72.6 nmol/L, 17.28 ppb) were achieved for the visual determination of uranium. The recognition mechanism, photophysical properties, analytical performance and cytotoxicity were systematically investigated, demonstrating high potential for fast risk assessment of uranium pollution in field and in vivo.
通过将两个三苯胺基团接枝到 2,6-双（氨甲基）吡啶上，构建了一种灵敏且生物相容的富氮探针，用于快速可视化铀检测。该探针具有出色的聚集诱导发射（AIE）性质，并具有与 U 选择性形成多齿螯合物的优点，已成功应用于复杂环境水样和活细胞中的铀可视化，展示了在宽有效的 pH 范围内对大量不同离子的出色抗干扰能力。该探针用于可视化铀的检测具有大的线性范围（1.0×10-9.0×10 mol/L）和低检测限（72.6 nmol/L，17.28 ppb）。系统研究了识别机制、光物理性质、分析性能和细胞毒性，表明该探针在现场和体内快速评估铀污染风险方面具有很高的潜力。
