Waller B F, Roberts W C
Am J Cardiol. 1985 Jan 1;55(1):65-71. doi: 10.1016/0002-9149(85)90301-7.
To assess the status of a saphenous vein (SV) excised for coronary artery bypass grafting (CABG), 3,394 cm of remnant SV from 402 patients who underwent CABG were examined. The SV remnants were 0.5 to 52 cm long (mean 8.4). They were sectioned into 5-mm-long segments, and the resulting 6,788 five-millimeter segments were examined histologically: 5,896 (87%) were narrowed 0 to 25% in cross-sectional area by fibrous tissue; 853 (12%) were narrowed 26 to 50%; 23 (0.6%), 51 to 75%, and 16 (0.4%) segments were narrowed 76 to 100%. Of the 16 segments severely narrowed, 7 (44%) were nearly totally occluded by fibrous tissue. In 17 patients who died within 24 hours of CABG, similar degrees of luminal narrowing were observed in remnant segments and in utilized segments of SV. Thus, significant preexisting luminal narrowing of SV used for CABG is infrequent. The intimal fibrous thickening is variable within the same vein when each 5-mm-long segment is analyzed; it is variable from 1 vein to another in the same patient, and it varies among patients.
为评估因冠状动脉旁路移植术（CABG）而切除的大隐静脉（SV）的状况，对402例行CABG患者的3394厘米大隐静脉残端进行了检查。大隐静脉残端长度为0.5至52厘米（平均8.4厘米）。将其切成5毫米长的节段，对得到的6788个5毫米节段进行组织学检查：5896个（87%）节段的横截面积因纤维组织而狭窄0至25%；853个（12%）节段狭窄26至50%；23个（0.6%）节段狭窄51至75%，16个（0.4%）节段狭窄76至100%。在16个严重狭窄的节段中，7个（44%）几乎完全被纤维组织阻塞。在CABG后24小时内死亡的17例患者中，大隐静脉残端节段和使用节段的管腔狭窄程度相似。因此，用于CABG的大隐静脉术前存在明显管腔狭窄的情况并不常见。当分析每个5毫米长的节段时，同一静脉内的内膜纤维增厚情况各不相同；在同一患者的不同静脉之间各不相同，且在患者之间也有所不同。
